Healthy aging and disease: Role for telomere biology?

Haidong Zhu, Matthew Belcher, Pim Van Der Harst

Research output: Contribution to journalReview article

100 Citations (Scopus)

Abstract

Aging is a biological process that affects most cells, organisms and species. Human aging is associated with increased susceptibility to a variety of chronic diseases, including cardiovascular disease, Type 2 diabetes, neurological diseases and cancer. Despite the remarkable progress made during the last two decades, our understanding of the biology of aging remains incomplete. Telomere biology has recently emerged as an important player in the aging and disease process.

Original languageEnglish (US)
Pages (from-to)427-440
Number of pages14
JournalClinical Science
Volume120
Issue number10
DOIs
StatePublished - May 1 2011

Fingerprint

Telomere
Biological Phenomena
Type 2 Diabetes Mellitus
Chronic Disease
Cardiovascular Diseases
Neoplasms

Keywords

  • Aging
  • Alzheimer's disease
  • Atherosclerosis
  • Heart failure
  • Longevity
  • Parkinson's disease
  • Telomerase
  • Telomere

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Healthy aging and disease : Role for telomere biology? / Zhu, Haidong; Belcher, Matthew; Van Der Harst, Pim.

In: Clinical Science, Vol. 120, No. 10, 01.05.2011, p. 427-440.

Research output: Contribution to journalReview article

Zhu, Haidong ; Belcher, Matthew ; Van Der Harst, Pim. / Healthy aging and disease : Role for telomere biology?. In: Clinical Science. 2011 ; Vol. 120, No. 10. pp. 427-440.
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