TY - JOUR
T1 - Heroin-Associated Rhabdomyolysis With Cardiac Involvement
AU - Schwartzfarb, Lanny
AU - Singh, Gurmukh
AU - Marcus, Douglas
PY - 1977/9
Y1 - 1977/9
N2 - A heroin addict had rhabdomyolysis with cardiac involvement. The patient was admitted with edema of the right leg and oliguria. Admission diagnoses were right iliofemoral thrombophlebitis, acute renal failure, and heroin addiction. Urinalysis was strongly positive for “blood” in the absence of hemolysis or marked hematocyturia, and a diagnosis of rhabdomyolysis was made. Peritoneal dialysis succeeded in lowering blood urea nitrogen and serum potassium levels, but the patient died on the fourth hospital day. Postmortem examination disclosed focal myocardial myolysis, diffuse rhabdomyolysis of the right soleus muscle, and acute renal tubular necrosis. Direct toxicity or hypersensitivity to heroin or an adulterant is considered in the pathogenesis of myolysis.
AB - A heroin addict had rhabdomyolysis with cardiac involvement. The patient was admitted with edema of the right leg and oliguria. Admission diagnoses were right iliofemoral thrombophlebitis, acute renal failure, and heroin addiction. Urinalysis was strongly positive for “blood” in the absence of hemolysis or marked hematocyturia, and a diagnosis of rhabdomyolysis was made. Peritoneal dialysis succeeded in lowering blood urea nitrogen and serum potassium levels, but the patient died on the fourth hospital day. Postmortem examination disclosed focal myocardial myolysis, diffuse rhabdomyolysis of the right soleus muscle, and acute renal tubular necrosis. Direct toxicity or hypersensitivity to heroin or an adulterant is considered in the pathogenesis of myolysis.
UR - http://www.scopus.com/inward/record.url?scp=0017604749&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017604749&partnerID=8YFLogxK
U2 - 10.1001/archinte.1977.03630210121035
DO - 10.1001/archinte.1977.03630210121035
M3 - Article
C2 - 901098
AN - SCOPUS:0017604749
SN - 0003-9926
VL - 137
SP - 1255
EP - 1257
JO - Archives of Internal Medicine
JF - Archives of Internal Medicine
IS - 9
ER -