Herpes simplex mimicking leukemia cutis

Mark H. Hassel, Jack L Lesher

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

We present a patient with chronic lymphocytic leukemia who developed a painful penile ulcer that was initially diagnosed as leukemia cutis, as evidenced hy an atypical leukemic infiltrate on biopsy. A Tzanck preparation was positive for multinucleated giant cells, and the diagnosis of herpes genitalis was confirmed by viral culture. In patients with hematologic malignancies, herpes simplex virus must be included in the differential diagnosis of ulcerative lesions. The histopathologic findings of inflammatory dermatoses in these patients may include an atypical infiltrate, because of the predominance of atypical inflammatory cells in the peripheral circulation.

Original languageEnglish (US)
Pages (from-to)367-371
Number of pages5
JournalJournal of the American Academy of Dermatology
Volume21
Issue number2
DOIs
StatePublished - Jan 1 1989

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Herpes Simplex
Leukemia
Herpes Genitalis
Hematologic Neoplasms
Simplexvirus
B-Cell Chronic Lymphocytic Leukemia
Giant Cells
Skin Diseases
Ulcer
Differential Diagnosis
Biopsy

ASJC Scopus subject areas

  • Dermatology

Cite this

Herpes simplex mimicking leukemia cutis. / Hassel, Mark H.; Lesher, Jack L.

In: Journal of the American Academy of Dermatology, Vol. 21, No. 2, 01.01.1989, p. 367-371.

Research output: Contribution to journalArticle

Hassel, Mark H. ; Lesher, Jack L. / Herpes simplex mimicking leukemia cutis. In: Journal of the American Academy of Dermatology. 1989 ; Vol. 21, No. 2. pp. 367-371.
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