High intensity focused ultrasound: The fundamentals, clinical applications and research trends

I. A.Shehata Elhelf, H. Albahar, U. Shah, A. Oto, E. Cressman, M. Almekkawy

Research output: Contribution to journalShort survey

20 Scopus citations

Abstract

Diagnostic ultrasound has been clinically used for decades. More recently, high intensity focused ultrasound (HIFU) has been developed for therapeutic use as a non-invasive technique for tissue ablation. HIFU is also being investigated for advanced applications at the cellular level. Under guidance by magnetic resonance or ultrasound imaging, HIFU can achieve precise biological effects in tissue with a high safety profile. In this article, we discuss the basic principles, advantages and limitations of HIFU. We will also address the food and drug administration (FDA) approved clinical applications in the United States and highlight active HIFU research with promising clinical outcomes.

Original languageEnglish (US)
Pages (from-to)349-359
Number of pages11
JournalDiagnostic and interventional imaging
Volume99
Issue number6
DOIs
StatePublished - Jun 2018
Externally publishedYes

Keywords

  • High intensity focused ultrasound (HIFU)
  • Immunomodulation
  • Interventional oncology
  • Temperature sensitive liposomes
  • Thermal ablation

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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