High occurrence of length heteroplasmy in domestic Bactrian camel (Camelus bactrianus)

Xiaohong He, Xiaofei Chen, Wenbin Zhang, Yabin Pu, Shen Song, Jianlin Han, Kunzhe Dong, Qianjun Zhao, Weijun Guan, Yuehui Ma, Lin Jiang

Research output: Contribution to journalArticlepeer-review


Heteroplasmy is the presence of more than one mitochondrial DNA (mtDNA) variant within a cell, tissue, or individual. In this study, sequence variation was investigated in the control region (CR) of mitochondrial DNA (mtDNA) from 135 individuals belonging to five primary domestic Bactrian camel breeds in China and Mongolia. Due to variation of the repeat unit G(T/C)(AC)n, length heteroplasmy was detected within each camel by direct sequencing and fragment analysis. A high occurrence of mtDNA heteroplasmy, up to 100 percentages was observed in five camel populations. Our study provides the first evidence of extensive length heteroplasmy in Bactrian camels.

Original languageEnglish (US)
Pages (from-to)851-854
Number of pages4
JournalMitochondrial DNA Part A: DNA Mapping, Sequencing, and Analysis
Issue number6
StatePublished - Nov 2 2017
Externally publishedYes


  • Bactrian camel
  • control region
  • length heteroplasmy
  • mitochondrial DNA

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics


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