TY - JOUR
T1 - High rates of exposure to tuberculosis patients among HIVinfected health care workers in Botswana
AU - Shin, S. S.
AU - Modongo, C.
AU - Zetola, N. M.
AU - Wang, Q.
AU - Phologolo, T.
AU - Kestler, M.
AU - Ho-Foster, A.
N1 - Funding Information:
This work was supported in part by funding from ACHAP, National Institutes of Health (NIH), Bethesda, MD, USA, grants (University of California Los Angeles [UCLA] Center for HIV Identification, Prevention, and Treatment, Los Angeles, CA: R01AI097045, K01AI118559, MH58107; UCLA Center for AIDS Research, Los Angeles, CA: 5P30AI028697; University of Pennsylvania Center for AIDS Research, Philadelphia, PA: P30AI045008; and National Center for Advancing Translational Sciences, Bethesda, MD, USA: UL1TR000124.
Funding Information:
This study drew from data collected by the TB/HIV Education and Care Program for Health Care Workers, a program funded by the African Comprehensive HIV/AIDS Partnerships (ACHAP). Partners critical to the program’s success include the Botswana National TB Program, the Workplace Wellness Program of the Department of HIV/AIDS Prevention and Care, Gaborone, and Botswana Ministry of Health, Gaborone, Botswana, workers from 30 participating health facilities in southern Botswana.
Publisher Copyright:
© 2018 The Union.
PY - 2018/4/1
Y1 - 2018/4/1
N2 - OBJECTIVE : To compare daily exposure to tuberculosis (TB) patients between HIV-infected and non-HIVinfected health care workers (HCWs), and examine the uptake of antiretroviral therapy (ART) and isoniazid preventive therapy (IPT) among HIV-infected HCWs in Botswana. DESIGN: We conducted a cross-sectional study among HCWs in 30 hospitals and clinics. We determined selfreported exposure frequency to TB patients and HIV status through in-person interviews. HCWs with unknown or negative HIV status were offered rapid HIV testing. Multivariable Poisson regression modeling with robust variance was used to estimate the association between HIV status and daily exposure to TB patients. RESULT S : Of 1877 participants enrolled, 1388 (73.9%) with complete data were included in this study. Among 277 (20.0%) HIV-infected participants, 14.3% were newly diagnosed, 57.8% were on ART, and 34.3% reported previously receiving IPT. Daily exposure to TB patients was reported by respectively 48.4% and 52.9% of HIV-infected and non-infected participants. After adjusting for sex, age, occupation, and department, the rates of daily TB exposure remained similar between HIV-infected and non-HIV-infected participants (prevalence ratio 0.96, 95%CI 0.85-1.08). CONCLUS IONS : We found similar rates of exposure to TB patients between HIV-infected and non-HIV-infected HCWs. Improved efforts are needed to reduce nosocomial exposure to TB among HIV-infected HCWs.
AB - OBJECTIVE : To compare daily exposure to tuberculosis (TB) patients between HIV-infected and non-HIVinfected health care workers (HCWs), and examine the uptake of antiretroviral therapy (ART) and isoniazid preventive therapy (IPT) among HIV-infected HCWs in Botswana. DESIGN: We conducted a cross-sectional study among HCWs in 30 hospitals and clinics. We determined selfreported exposure frequency to TB patients and HIV status through in-person interviews. HCWs with unknown or negative HIV status were offered rapid HIV testing. Multivariable Poisson regression modeling with robust variance was used to estimate the association between HIV status and daily exposure to TB patients. RESULT S : Of 1877 participants enrolled, 1388 (73.9%) with complete data were included in this study. Among 277 (20.0%) HIV-infected participants, 14.3% were newly diagnosed, 57.8% were on ART, and 34.3% reported previously receiving IPT. Daily exposure to TB patients was reported by respectively 48.4% and 52.9% of HIV-infected and non-infected participants. After adjusting for sex, age, occupation, and department, the rates of daily TB exposure remained similar between HIV-infected and non-HIV-infected participants (prevalence ratio 0.96, 95%CI 0.85-1.08). CONCLUS IONS : We found similar rates of exposure to TB patients between HIV-infected and non-HIV-infected HCWs. Improved efforts are needed to reduce nosocomial exposure to TB among HIV-infected HCWs.
KW - Infection control
KW - Infectious disease transmission
KW - Nosocomial transmission
KW - Social stigma
KW - Workplace
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U2 - 10.5588/ijtld.17.0376
DO - 10.5588/ijtld.17.0376
M3 - Article
C2 - 29562982
AN - SCOPUS:85044971280
SN - 1027-3719
VL - 22
SP - 366
EP - 370
JO - International Journal of Tuberculosis and Lung Disease
JF - International Journal of Tuberculosis and Lung Disease
IS - 4
ER -