Hippocampal contribution to verbal recent memory following dominant-hemisphere temporal lobectomy

D. W. Loring, Gregory P Lee, K. J. Meador, J. R. Smith, R. C. Martin, A. B. Ackell, H. F. Flanigin

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

The effects of hippocampal encroachment in the language dominant-hemisphere were studied in 41 patients who underwent previous temporal lobectomy (TL). Patients undergoing dominant-hemisphere TL including anterior hippocampus (n = 13) performed significantly worse than nondominant TL patients (n = 16) on a verbal learning test (Selective Reminding; p ≤ .00001), thereby confirming the sensitivity of this procedure to lateralized temporal-lobe dysfunction. However, no significant difference was present on this or other primary measures of material-specific memory when contrasting dominant TL patients in whom the anterior hippocampus was spared (n = 12) to those in whom anterior hippocampus was resected. These data suggest that more extensive and posterior mesial temporal-lobe resection is not necessarily associated with a greater verbal material-specific memory deficit following dominant-hemisphere temporal lobectomy.

Original languageEnglish (US)
Pages (from-to)575-586
Number of pages12
JournalJournal of Clinical and Experimental Neuropsychology
Volume13
Issue number4
DOIs
StatePublished - Jan 1 1991

Fingerprint

Hippocampus
Temporal Lobe
Anterior Temporal Lobectomy
Verbal Learning
Memory Disorders
Language

ASJC Scopus subject areas

  • Clinical Psychology
  • Neurology
  • Clinical Neurology

Cite this

Loring, D. W., Lee, G. P., Meador, K. J., Smith, J. R., Martin, R. C., Ackell, A. B., & Flanigin, H. F. (1991). Hippocampal contribution to verbal recent memory following dominant-hemisphere temporal lobectomy. Journal of Clinical and Experimental Neuropsychology, 13(4), 575-586. https://doi.org/10.1080/01688639108401072

Hippocampal contribution to verbal recent memory following dominant-hemisphere temporal lobectomy. / Loring, D. W.; Lee, Gregory P; Meador, K. J.; Smith, J. R.; Martin, R. C.; Ackell, A. B.; Flanigin, H. F.

In: Journal of Clinical and Experimental Neuropsychology, Vol. 13, No. 4, 01.01.1991, p. 575-586.

Research output: Contribution to journalArticle

Loring, D. W. ; Lee, Gregory P ; Meador, K. J. ; Smith, J. R. ; Martin, R. C. ; Ackell, A. B. ; Flanigin, H. F. / Hippocampal contribution to verbal recent memory following dominant-hemisphere temporal lobectomy. In: Journal of Clinical and Experimental Neuropsychology. 1991 ; Vol. 13, No. 4. pp. 575-586.
@article{fed02fceaeb44c44a61d9b3189bb3295,
title = "Hippocampal contribution to verbal recent memory following dominant-hemisphere temporal lobectomy",
abstract = "The effects of hippocampal encroachment in the language dominant-hemisphere were studied in 41 patients who underwent previous temporal lobectomy (TL). Patients undergoing dominant-hemisphere TL including anterior hippocampus (n = 13) performed significantly worse than nondominant TL patients (n = 16) on a verbal learning test (Selective Reminding; p ≤ .00001), thereby confirming the sensitivity of this procedure to lateralized temporal-lobe dysfunction. However, no significant difference was present on this or other primary measures of material-specific memory when contrasting dominant TL patients in whom the anterior hippocampus was spared (n = 12) to those in whom anterior hippocampus was resected. These data suggest that more extensive and posterior mesial temporal-lobe resection is not necessarily associated with a greater verbal material-specific memory deficit following dominant-hemisphere temporal lobectomy.",
author = "Loring, {D. W.} and Lee, {Gregory P} and Meador, {K. J.} and Smith, {J. R.} and Martin, {R. C.} and Ackell, {A. B.} and Flanigin, {H. F.}",
year = "1991",
month = "1",
day = "1",
doi = "10.1080/01688639108401072",
language = "English (US)",
volume = "13",
pages = "575--586",
journal = "Journal of Clinical and Experimental Neuropsychology",
issn = "0168-8634",
publisher = "Psychology Press Ltd",
number = "4",

}

TY - JOUR

T1 - Hippocampal contribution to verbal recent memory following dominant-hemisphere temporal lobectomy

AU - Loring, D. W.

AU - Lee, Gregory P

AU - Meador, K. J.

AU - Smith, J. R.

AU - Martin, R. C.

AU - Ackell, A. B.

AU - Flanigin, H. F.

PY - 1991/1/1

Y1 - 1991/1/1

N2 - The effects of hippocampal encroachment in the language dominant-hemisphere were studied in 41 patients who underwent previous temporal lobectomy (TL). Patients undergoing dominant-hemisphere TL including anterior hippocampus (n = 13) performed significantly worse than nondominant TL patients (n = 16) on a verbal learning test (Selective Reminding; p ≤ .00001), thereby confirming the sensitivity of this procedure to lateralized temporal-lobe dysfunction. However, no significant difference was present on this or other primary measures of material-specific memory when contrasting dominant TL patients in whom the anterior hippocampus was spared (n = 12) to those in whom anterior hippocampus was resected. These data suggest that more extensive and posterior mesial temporal-lobe resection is not necessarily associated with a greater verbal material-specific memory deficit following dominant-hemisphere temporal lobectomy.

AB - The effects of hippocampal encroachment in the language dominant-hemisphere were studied in 41 patients who underwent previous temporal lobectomy (TL). Patients undergoing dominant-hemisphere TL including anterior hippocampus (n = 13) performed significantly worse than nondominant TL patients (n = 16) on a verbal learning test (Selective Reminding; p ≤ .00001), thereby confirming the sensitivity of this procedure to lateralized temporal-lobe dysfunction. However, no significant difference was present on this or other primary measures of material-specific memory when contrasting dominant TL patients in whom the anterior hippocampus was spared (n = 12) to those in whom anterior hippocampus was resected. These data suggest that more extensive and posterior mesial temporal-lobe resection is not necessarily associated with a greater verbal material-specific memory deficit following dominant-hemisphere temporal lobectomy.

UR - http://www.scopus.com/inward/record.url?scp=0025820385&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025820385&partnerID=8YFLogxK

U2 - 10.1080/01688639108401072

DO - 10.1080/01688639108401072

M3 - Article

VL - 13

SP - 575

EP - 586

JO - Journal of Clinical and Experimental Neuropsychology

JF - Journal of Clinical and Experimental Neuropsychology

SN - 0168-8634

IS - 4

ER -