Histone deacetylase inhibitors suppress TF-κB-dependent agonist-driven tissue factor expression in endothelial cells and monocytes

Medicine & Life Sciences

• Histone Deacetylase Inhibitors 66%
• Thromboplastin 63%
• Monocytes 47%
• Endothelial Cells 41%
• trichostatin A 37%
• Tumor Necrosis Factor-alpha 13%
• Chromatin Immunoprecipitation 10%
• Human Umbilical Vein Endothelial Cells 10%
• Intercellular Adhesion Molecule-1 9%
• apicidin 8%
• Lipopolysaccharides 8%
• entinostat 7%
• 3'-(1-butylphosphoryl)adenosine 7%
• Thioglycolates 6%
• Butyrates 5%
• Butyric Acid 5%
• E-Selectin 5%
• Histone Deacetylases 5%
• Peritoneal Macrophages 5%
• Valproic Acid 5%
• Electrophoretic Mobility Shift Assay 5%
• Acetylation 4%
• Interleukin-1 4%
• Histones 4%
• Luciferases 4%
• Small Interfering RNA 3%
• Blood Cells 3%
• Binding Sites 3%
• Transcription Factors 3%
• Gene Expression 2%
• Messenger RNA 2%
• In Vitro Techniques 2%
• Proteins 1%
• Therapeutics 0%

Chemical Compounds

• Trichostatin A 100%
• Histone 60%
• Lipopolysaccharide 20%
• Sodium Butyrate 16%
• Thrombotic 14%
• Valproic Acid 13%
• Small Interfering RNA 13%
• Butyrate 11%
• Heterodimer 10%
• Acetylation 9%
• Agonist 9%
• Disorder 8%
• Binding Site 6%
• Probe 5%
• Protein 3%