HSV-2 ICP34.5 protein modulates herpes simplex virus glycoprotein processing

Somik Chatterjee; Jason W. Wang; Mary J. Cismowski; John R. Bower; Kenneth Steven Rosenthal

doi:10.1007/s00705-009-0341-9

HSV-2 ICP34.5 protein modulates herpes simplex virus glycoprotein processing

Somik Chatterjee, Jason W. Wang, Mary J. Cismowski, John R. Bower, Kenneth Steven Rosenthal

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The ICP34.5 gene from HSV-2 strain 333 was cloned and, when expressed in Vero cells, enhanced the efficiency and extent of glycoprotein processing of glycoprotein C (gC1), a representative viral glycoprotein, during infection with HSV-1 SP7. The ICP34.5 from HSV-1 SP7 limits the extent and efficiency of viral glycoprotein processing. The ability of the HSV-2 ICP34.5 protein to enhance the efficiency and extent of HSV-1 SP7 glycoprotein processing indicates that modulation of viral glycoprotein processing is also a property of the HSV-2 ICP34.5 protein.

Original language	English (US)
Pages (from-to)	661-663
Number of pages	3
Journal	Archives of Virology
Volume	154
Issue number	4
DOIs	https://doi.org/10.1007/s00705-009-0341-9
State	Published - Apr 2009
Externally published	Yes

ASJC Scopus subject areas

Virology

Access to Document

10.1007/s00705-009-0341-9

Cite this

@article{4756ff5efb8d49f886d29e533b9b48f7,

title = "HSV-2 ICP34.5 protein modulates herpes simplex virus glycoprotein processing",

abstract = "The ICP34.5 gene from HSV-2 strain 333 was cloned and, when expressed in Vero cells, enhanced the efficiency and extent of glycoprotein processing of glycoprotein C (gC1), a representative viral glycoprotein, during infection with HSV-1 SP7. The ICP34.5 from HSV-1 SP7 limits the extent and efficiency of viral glycoprotein processing. The ability of the HSV-2 ICP34.5 protein to enhance the efficiency and extent of HSV-1 SP7 glycoprotein processing indicates that modulation of viral glycoprotein processing is also a property of the HSV-2 ICP34.5 protein.",

author = "Somik Chatterjee and Wang, {Jason W.} and Cismowski, {Mary J.} and Bower, {John R.} and Rosenthal, {Kenneth Steven}",

year = "2009",

month = apr,

doi = "10.1007/s00705-009-0341-9",

language = "English (US)",

volume = "154",

pages = "661--663",

journal = "Archives of Virology",

issn = "0304-8608",

publisher = "Springer Wien",

number = "4",

}

TY - JOUR

T1 - HSV-2 ICP34.5 protein modulates herpes simplex virus glycoprotein processing

AU - Chatterjee, Somik

AU - Wang, Jason W.

AU - Cismowski, Mary J.

AU - Bower, John R.

AU - Rosenthal, Kenneth Steven

PY - 2009/4

Y1 - 2009/4

N2 - The ICP34.5 gene from HSV-2 strain 333 was cloned and, when expressed in Vero cells, enhanced the efficiency and extent of glycoprotein processing of glycoprotein C (gC1), a representative viral glycoprotein, during infection with HSV-1 SP7. The ICP34.5 from HSV-1 SP7 limits the extent and efficiency of viral glycoprotein processing. The ability of the HSV-2 ICP34.5 protein to enhance the efficiency and extent of HSV-1 SP7 glycoprotein processing indicates that modulation of viral glycoprotein processing is also a property of the HSV-2 ICP34.5 protein.

AB - The ICP34.5 gene from HSV-2 strain 333 was cloned and, when expressed in Vero cells, enhanced the efficiency and extent of glycoprotein processing of glycoprotein C (gC1), a representative viral glycoprotein, during infection with HSV-1 SP7. The ICP34.5 from HSV-1 SP7 limits the extent and efficiency of viral glycoprotein processing. The ability of the HSV-2 ICP34.5 protein to enhance the efficiency and extent of HSV-1 SP7 glycoprotein processing indicates that modulation of viral glycoprotein processing is also a property of the HSV-2 ICP34.5 protein.

UR - http://www.scopus.com/inward/record.url?scp=64249171383&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=64249171383&partnerID=8YFLogxK

U2 - 10.1007/s00705-009-0341-9

DO - 10.1007/s00705-009-0341-9

M3 - Article

C2 - 19267180

AN - SCOPUS:64249171383

SN - 0304-8608

VL - 154

SP - 661

EP - 663

JO - Archives of Virology

JF - Archives of Virology

IS - 4

ER -

HSV-2 ICP34.5 protein modulates herpes simplex virus glycoprotein processing

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this