Human heart, lung and heart-lung transplantation.

Carsten Schroeder, Paolo Macchiarini

Research output: Contribution to journalReview article


Compared to the other organ transplantations, lung and heart-lung transplantations have the following peculiarities: (1) bacterial colonization of the bronchi or lung parenchyma is almost constant because of the contact of donor's and recipient's lungs to the air through the intubation tube; (2) the lung is a particularly fragile organ and sensitive to the hemodynamic modifications in the donor following brain death; (3) the lung is the only organ transplanted without systemic revascularization, which increases the risks of bronchial ischemia, bronchomalacia, and mucociliary dysfunction; and (4) the lung has a large amount of lymphoid tissue, rendering it particularly immunogenic.

Original languageEnglish (US)
Pages (from-to)178-185
Number of pages8
JournalSurgical technology international
StatePublished - Jan 1 2002
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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    Schroeder, C., & Macchiarini, P. (2002). Human heart, lung and heart-lung transplantation. Surgical technology international, 10, 178-185.