Hydrolysis of functional monomers in a single-bottle self-etching primer - Correlation of 13C NMR and TEM findings

N. Nishiyama, F. R. Tay, K. Fujita, D. H. Pashley, K. Ikemura, N. Hiraishi, N. M. King

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Self-etching primers/adhesives that combine acidic methacrylate monomers with water in a single bottle are hydrolytically unstable and require refrigeration to extend their shelf-lives. This study tested the null hypothesis that one year of intermittent refrigeration of a 4-MET-containing simplified self-etching primer does not result in hydrolytic changes that are identifiable by transmission electron microscopy and 13C NMR spectroscopy. Human dentin was bonded with UniFil Bond immediately after being unpacked, or after one year of intermittent refrigeration at 4°C. Fresh and aged primers were analyzed by NMR for chemical changes. Ultrastructural observations indicated that there was an augmentation in etching capacity of the aged adhesive that was not accompanied by resin infiltration or effective polymerization. New NMR peaks detected from the aged ethanol-based primer confirmed that degradation occurred initially via esterification with ethanol, followed by hydrolysis of both ester groups in the 4-MET. Hydrolysis of functional methacrylate monomers occurs despite intermittent refrigeration.

Original languageEnglish (US)
Pages (from-to)422-426
Number of pages5
JournalJournal of Dental Research
Volume85
Issue number5
DOIs
StatePublished - May 1 2006

Fingerprint

Refrigeration
Hydrolysis
Methacrylates
Adhesives
Ethanol
Esterification
Dentin
Transmission Electron Microscopy
Polymerization
Esters
Magnetic Resonance Spectroscopy
Carbon-13 Magnetic Resonance Spectroscopy
Water

Keywords

  • 4-MET
  • Hydrolysis
  • Nuclear magnetic resonance
  • Self-etching
  • Single-bottle

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Hydrolysis of functional monomers in a single-bottle self-etching primer - Correlation of 13C NMR and TEM findings. / Nishiyama, N.; Tay, F. R.; Fujita, K.; Pashley, D. H.; Ikemura, K.; Hiraishi, N.; King, N. M.

In: Journal of Dental Research, Vol. 85, No. 5, 01.05.2006, p. 422-426.

Research output: Contribution to journalArticle

Nishiyama, N. ; Tay, F. R. ; Fujita, K. ; Pashley, D. H. ; Ikemura, K. ; Hiraishi, N. ; King, N. M. / Hydrolysis of functional monomers in a single-bottle self-etching primer - Correlation of 13C NMR and TEM findings. In: Journal of Dental Research. 2006 ; Vol. 85, No. 5. pp. 422-426.
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