TY - JOUR
T1 - Hyperostosis - an unusual radiographic presentation of myelodysplastic syndrome transformed to acute myeloid leukemia
AU - Franco, Arie
AU - Lewis, Kristopher N.
AU - Blackmon, Joshua M.
AU - Manaloor, Elizabeth J.
PY - 2010
Y1 - 2010
N2 - Acute myeloid leukemia (AML) is also referred to non-lymphocytic leukemia in the literature. It comprises about 15% of the childhood leukemia. There are multiple subtypes of AML from M0-M7 with approximately 45% of the cases being M0-M2 and the remaining subtypes being rare. The definitive diagnosis relies on bone marrow biopsy showing bone marrow infiltration with leukemic cells. We describe a rare radiographic presentation of myelodysplastic syndrome (MDS) transformed to AML in an 8 month old boy who presented with a orbital wall fracture, periosteal reaction, and mixed lytic and sclerotic lesions.
AB - Acute myeloid leukemia (AML) is also referred to non-lymphocytic leukemia in the literature. It comprises about 15% of the childhood leukemia. There are multiple subtypes of AML from M0-M7 with approximately 45% of the cases being M0-M2 and the remaining subtypes being rare. The definitive diagnosis relies on bone marrow biopsy showing bone marrow infiltration with leukemic cells. We describe a rare radiographic presentation of myelodysplastic syndrome (MDS) transformed to AML in an 8 month old boy who presented with a orbital wall fracture, periosteal reaction, and mixed lytic and sclerotic lesions.
KW - Acute myeloid leukemia
KW - Hyperostosis
KW - Myelodysplastic syndrome
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U2 - 10.3941/jrcr.v4i11.569
DO - 10.3941/jrcr.v4i11.569
M3 - Article
C2 - 22470698
AN - SCOPUS:78649487702
SN - 1943-0922
VL - 4
SP - 18
EP - 25
JO - Journal of Radiology Case Reports
JF - Journal of Radiology Case Reports
IS - 11
ER -