Hyperostosis - an unusual radiographic presentation of myelodysplastic syndrome transformed to acute myeloid leukemia

Arie Franco, Kristopher N. Lewis, Joshua M. Blackmon, Elizabeth J. Manaloor

Research output: Contribution to journalArticle

2 Scopus citations


Acute myeloid leukemia (AML) is also referred to non-lymphocytic leukemia in the literature. It comprises about 15% of the childhood leukemia. There are multiple subtypes of AML from M0-M7 with approximately 45% of the cases being M0-M2 and the remaining subtypes being rare. The definitive diagnosis relies on bone marrow biopsy showing bone marrow infiltration with leukemic cells. We describe a rare radiographic presentation of myelodysplastic syndrome (MDS) transformed to AML in an 8 month old boy who presented with a orbital wall fracture, periosteal reaction, and mixed lytic and sclerotic lesions.

Original languageEnglish (US)
Pages (from-to)18-25
Number of pages8
JournalJournal of Radiology Case Reports
Issue number11
Publication statusPublished - Dec 2 2010



  • Acute myeloid leukemia
  • Hyperostosis
  • Myelodysplastic syndrome

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this