Idiopathic ulcerative laryngitis

C. Blake Simpson, Lucian Sulica, Gregory N. Postma, Clark A. Rosen, Milan R. Amin, Albert L. Merati, Mark S. Courey, Vatsal Patel, Michael M. Johns

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objectives/Hypothesis: Idiopathic ulcerative laryngitis (IUL) is a distinct, clinical entity that presents after a prolonged upper respiratory infection with cough. It is characterized by the development of bilateral ulcerations of the mid-membranous vocal folds followed by a protracted course of healing. The purpose of this review was to characterize the typical patient presentation, clinical findings, and prognosis. Study Design: Multi-institutional retrospective review Methods: Retrospective review of charts and videostroboscopic exams from patients with IUL at eight institutions. Results: Fifteen cases met the criteria for IUL and were included in the study. The mean age of the patients was 49 years, and 93% were female. All patients were nonsmokers. Multiple medical interventions were employed by the treating otolaryngologist during the course of the disease, none of which resulted in acute resolution of the ulcerations. The average time from initial presentation to resolution of the disease was 3.3 months. All of the patients reported that their voice was improved after resolution of the disease process. However, in the majority of the patients (60%) there were persistent vibratory abnormalities after resolution of the ulcerations. Conclusions: This is the first multi-institutional study to define the complete disease course of IUL and to establish diagnostic criteria. IUL is a rare yet well-recognized clinical entity; however, there is no established etiology for this condition and no definitive treatments have emerged. Further study is needed to establish the etiology/risk factors of this condition and to determine optimal medical management.

Original languageEnglish (US)
Pages (from-to)1023-1026
Number of pages4
JournalLaryngoscope
Volume121
Issue number5
DOIs
StatePublished - May 1 2011

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Laryngitis
Vocal Cords
Cough
Respiratory Tract Infections

Keywords

  • Laryngitis
  • ulcer

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Simpson, C. B., Sulica, L., Postma, G. N., Rosen, C. A., Amin, M. R., Merati, A. L., ... Johns, M. M. (2011). Idiopathic ulcerative laryngitis. Laryngoscope, 121(5), 1023-1026. https://doi.org/10.1002/lary.21659

Idiopathic ulcerative laryngitis. / Simpson, C. Blake; Sulica, Lucian; Postma, Gregory N.; Rosen, Clark A.; Amin, Milan R.; Merati, Albert L.; Courey, Mark S.; Patel, Vatsal; Johns, Michael M.

In: Laryngoscope, Vol. 121, No. 5, 01.05.2011, p. 1023-1026.

Research output: Contribution to journalArticle

Simpson, CB, Sulica, L, Postma, GN, Rosen, CA, Amin, MR, Merati, AL, Courey, MS, Patel, V & Johns, MM 2011, 'Idiopathic ulcerative laryngitis', Laryngoscope, vol. 121, no. 5, pp. 1023-1026. https://doi.org/10.1002/lary.21659
Simpson CB, Sulica L, Postma GN, Rosen CA, Amin MR, Merati AL et al. Idiopathic ulcerative laryngitis. Laryngoscope. 2011 May 1;121(5):1023-1026. https://doi.org/10.1002/lary.21659
Simpson, C. Blake ; Sulica, Lucian ; Postma, Gregory N. ; Rosen, Clark A. ; Amin, Milan R. ; Merati, Albert L. ; Courey, Mark S. ; Patel, Vatsal ; Johns, Michael M. / Idiopathic ulcerative laryngitis. In: Laryngoscope. 2011 ; Vol. 121, No. 5. pp. 1023-1026.
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