Impaired stress-induced pressure natriuresis increases cardiovascular load in African American youths

Gregory A Harshfield, Martha E. Wilson, Coral Hanevold, Kakota Gaston Kapuku, Lynne Mackey, Delores Gillis, Frank A. Treiber

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Background: We hypothesized that impaired stress-induced pressure natriuresis increases blood pressure (BP) load. Methods: The 118 African American youths were brought into similar levels of sodium balance. The protocol consisted of a 2-h baseline period, a 1-h stress period (competitive video games), and a 2-h recovery period. Results: Normal pressure natriuresis (n = 80) resulted from a resistance-mediated (r = 0.23; P < .03) increase in BP (P < .001). In contrast, impaired pressure natriuresis (n = 38), leading to an extended period of elevated BP (P < .05), resulted from a volume-mediated (r = 0.55; P < .002) increase, in BP (P < .001). Conclusions: Impaired stress-induced pressure natriuresis may contribute to the development of essential hypertension, particularly in African Americans. Am J Hypertens 2002;15:903-906

Original languageEnglish (US)
Pages (from-to)903-906
Number of pages4
JournalAmerican journal of hypertension
Volume15
Issue number10 I
DOIs
StatePublished - Oct 1 2002

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Natriuresis
African Americans
Blood Pressure
Pressure
Video Games
Sodium

Keywords

  • African Americans
  • Blood pressure
  • Race
  • Sodium
  • Stress

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Impaired stress-induced pressure natriuresis increases cardiovascular load in African American youths. / Harshfield, Gregory A; Wilson, Martha E.; Hanevold, Coral; Kapuku, Kakota Gaston; Mackey, Lynne; Gillis, Delores; Treiber, Frank A.

In: American journal of hypertension, Vol. 15, No. 10 I, 01.10.2002, p. 903-906.

Research output: Contribution to journalArticle

Harshfield, Gregory A ; Wilson, Martha E. ; Hanevold, Coral ; Kapuku, Kakota Gaston ; Mackey, Lynne ; Gillis, Delores ; Treiber, Frank A. / Impaired stress-induced pressure natriuresis increases cardiovascular load in African American youths. In: American journal of hypertension. 2002 ; Vol. 15, No. 10 I. pp. 903-906.
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AU - Gillis, Delores

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