TY - GEN
T1 - Improved cardiac Manganese-Enhanced MRI (MEMRI) with T1 mapping in rodent
AU - Hu, Tom C.C.
AU - Chuang, Kai Hsiang
AU - Yanasak, Nathan
AU - Koretsky, Alan P.
PY - 2007/12/1
Y1 - 2007/12/1
N2 - Manganese ion (Mn2+) is an intracellular contrast agent that enters viable myocardial cells via voltage gated calcium channels. Along with its T1 shortening effect and relatively long half-life in cells, it becomes a very useful molecular contrast agent to study calcium influx. One major concern for using Mn2+ is getting quantitative information over a range of concentrations. Therefore, in this study, a T1 mapping method has been implemented for cardiac manganese-enhanced MRI (MEMRI) to increase the sensitivity and enable the quantitative estimate of a range of concentrations.
AB - Manganese ion (Mn2+) is an intracellular contrast agent that enters viable myocardial cells via voltage gated calcium channels. Along with its T1 shortening effect and relatively long half-life in cells, it becomes a very useful molecular contrast agent to study calcium influx. One major concern for using Mn2+ is getting quantitative information over a range of concentrations. Therefore, in this study, a T1 mapping method has been implemented for cardiac manganese-enhanced MRI (MEMRI) to increase the sensitivity and enable the quantitative estimate of a range of concentrations.
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U2 - 10.1109/NEBC.2007.4413285
DO - 10.1109/NEBC.2007.4413285
M3 - Conference contribution
AN - SCOPUS:48749121545
SN - 1424410339
SN - 9781424410330
T3 - Bioengineering, Proceedings of the Northeast Conference
SP - 73
EP - 74
BT - 33rd Annual Northeast Bioengineering Conference - Engineering Innovations in Life Sciences and Healthcare, NEBC
T2 - 33rd Annual Northeast Bioengineering Conference, NEBC
Y2 - 10 March 2007 through 11 March 2007
ER -