Improved cardiac Manganese-Enhanced MRI (MEMRI) with T1 mapping in rodent

Tom C.C. Hu, Kai Hsiang Chuang, Nathan Yanasak, Alan P. Koretsky

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Manganese ion (Mn2+) is an intracellular contrast agent that enters viable myocardial cells via voltage gated calcium channels. Along with its T1 shortening effect and relatively long half-life in cells, it becomes a very useful molecular contrast agent to study calcium influx. One major concern for using Mn2+ is getting quantitative information over a range of concentrations. Therefore, in this study, a T1 mapping method has been implemented for cardiac manganese-enhanced MRI (MEMRI) to increase the sensitivity and enable the quantitative estimate of a range of concentrations.

Original languageEnglish (US)
Title of host publication33rd Annual Northeast Bioengineering Conference - Engineering Innovations in Life Sciences and Healthcare, NEBC
Pages73-74
Number of pages2
DOIs
StatePublished - Dec 1 2007
Event33rd Annual Northeast Bioengineering Conference, NEBC - Stony Brook, NY, United States
Duration: Mar 10 2007Mar 11 2007

Publication series

NameBioengineering, Proceedings of the Northeast Conference
ISSN (Print)1071-121X

Other

Other33rd Annual Northeast Bioengineering Conference, NEBC
CountryUnited States
CityStony Brook, NY
Period3/10/073/11/07

ASJC Scopus subject areas

  • Bioengineering

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