Abstract
Manganese ion (Mn2+) is an intracellular contrast agent that enters viable myocardial cells via voltage gated calcium channels. Along with its T1 shortening effect and relatively long half-life in cells, it becomes a very useful molecular contrast agent to study calcium influx. One major concern for using Mn2+ is getting quantitative information over a range of concentrations. Therefore, in this study, a T1 mapping method has been implemented for cardiac manganese-enhanced MRI (MEMRI) to increase the sensitivity and enable the quantitative estimate of a range of concentrations.
| Original language | English (US) |
|---|---|
| Title of host publication | 33rd Annual Northeast Bioengineering Conference - Engineering Innovations in Life Sciences and Healthcare, NEBC |
| Pages | 73-74 |
| Number of pages | 2 |
| DOIs | |
| State | Published - Dec 1 2007 |
| Event | 33rd Annual Northeast Bioengineering Conference, NEBC - Stony Brook, NY, United States Duration: Mar 10 2007 → Mar 11 2007 |
Publication series
| Name | Bioengineering, Proceedings of the Northeast Conference |
|---|---|
| ISSN (Print) | 1071-121X |
Other
| Other | 33rd Annual Northeast Bioengineering Conference, NEBC |
|---|---|
| Country | United States |
| City | Stony Brook, NY |
| Period | 3/10/07 → 3/11/07 |
Fingerprint
ASJC Scopus subject areas
- Bioengineering
Cite this
Improved cardiac Manganese-Enhanced MRI (MEMRI) with T1 mapping in rodent. / Hu, Tom C.C.; Chuang, Kai Hsiang; Yanasak, Nathan; Koretsky, Alan P.
33rd Annual Northeast Bioengineering Conference - Engineering Innovations in Life Sciences and Healthcare, NEBC. 2007. p. 73-74 4413285 (Bioengineering, Proceedings of the Northeast Conference).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Improved cardiac Manganese-Enhanced MRI (MEMRI) with T1 mapping in rodent
AU - Hu, Tom C.C.
AU - Chuang, Kai Hsiang
AU - Yanasak, Nathan
AU - Koretsky, Alan P.
PY - 2007/12/1
Y1 - 2007/12/1
N2 - Manganese ion (Mn2+) is an intracellular contrast agent that enters viable myocardial cells via voltage gated calcium channels. Along with its T1 shortening effect and relatively long half-life in cells, it becomes a very useful molecular contrast agent to study calcium influx. One major concern for using Mn2+ is getting quantitative information over a range of concentrations. Therefore, in this study, a T1 mapping method has been implemented for cardiac manganese-enhanced MRI (MEMRI) to increase the sensitivity and enable the quantitative estimate of a range of concentrations.
AB - Manganese ion (Mn2+) is an intracellular contrast agent that enters viable myocardial cells via voltage gated calcium channels. Along with its T1 shortening effect and relatively long half-life in cells, it becomes a very useful molecular contrast agent to study calcium influx. One major concern for using Mn2+ is getting quantitative information over a range of concentrations. Therefore, in this study, a T1 mapping method has been implemented for cardiac manganese-enhanced MRI (MEMRI) to increase the sensitivity and enable the quantitative estimate of a range of concentrations.
UR - http://www.scopus.com/inward/record.url?scp=48749121545&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=48749121545&partnerID=8YFLogxK
U2 - 10.1109/NEBC.2007.4413285
DO - 10.1109/NEBC.2007.4413285
M3 - Conference contribution
AN - SCOPUS:48749121545
SN - 1424410339
SN - 9781424410330
T3 - Bioengineering, Proceedings of the Northeast Conference
SP - 73
EP - 74
BT - 33rd Annual Northeast Bioengineering Conference - Engineering Innovations in Life Sciences and Healthcare, NEBC
ER -