TY - JOUR
T1 - In vitro study assessing the antibacterial activity of three silver-impregnated/coated mechanical valve needleless connectors after blood exposure
AU - Chernecky, Cynthia C.
AU - Waller, Jennifer L.
AU - Jarvis, William R.
N1 - Funding Information:
The laboratory testing was funded by RyMed Technologies, Inc (Franklin, TN), and conducted by an independent laboratory, Nelson Laboratories, Inc, Salt Lake City, UT. All protocols and test data were supplied directly to the authors. No data were omitted or modified. RyMed purchased and supplied the sterile test needleless connectors for testing to Nelson Laboratories, Inc. All products were obtained from the marketplace and were not modified or manipulated in any manner before the testing. None of the authors received any funding for preparation of this manuscript.
PY - 2013/3
Y1 - 2013/3
N2 - This in vitro study's purpose was to assess antibacterial activity of 3 different connectors: V-Link (Baxter, Deerfield, IL), Ultrasite Ag (B. Braun, Bethlehem, PA), and MaxGuard (CareFusion, Ontario, CA), impregnated with silver nanoparticles after blood exposure. All 3 silver-coated/impregnated connectors grew Staphylococcus aureus and Staphylococcus epidermidis. Log reduction of bacteria was not significant (range, +0.19 to -1.82). There was substantial bacterial recovery from all 3 connectors (mean ranges, 2.09 × 10 7 to 4.00 × 108) indicating that, once blood comes in contact with silver-coated/impregnated needleless connectors, their antibacterial activity is significantly reduced.
AB - This in vitro study's purpose was to assess antibacterial activity of 3 different connectors: V-Link (Baxter, Deerfield, IL), Ultrasite Ag (B. Braun, Bethlehem, PA), and MaxGuard (CareFusion, Ontario, CA), impregnated with silver nanoparticles after blood exposure. All 3 silver-coated/impregnated connectors grew Staphylococcus aureus and Staphylococcus epidermidis. Log reduction of bacteria was not significant (range, +0.19 to -1.82). There was substantial bacterial recovery from all 3 connectors (mean ranges, 2.09 × 10 7 to 4.00 × 108) indicating that, once blood comes in contact with silver-coated/impregnated needleless connectors, their antibacterial activity is significantly reduced.
KW - Bacteremia
KW - Bloodstream infections
KW - Central line-associated bloodstream infections
KW - Intravenous
UR - http://www.scopus.com/inward/record.url?scp=84875372559&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84875372559&partnerID=8YFLogxK
U2 - 10.1016/j.ajic.2012.03.020
DO - 10.1016/j.ajic.2012.03.020
M3 - Article
C2 - 22863121
AN - SCOPUS:84875372559
SN - 0196-6553
VL - 41
SP - 278
EP - 280
JO - American Journal of Infection Control
JF - American Journal of Infection Control
IS - 3
ER -
