This in vitro study's purpose was to assess antibacterial activity of 3 different connectors: V-Link (Baxter, Deerfield, IL), Ultrasite Ag (B. Braun, Bethlehem, PA), and MaxGuard (CareFusion, Ontario, CA), impregnated with silver nanoparticles after blood exposure. All 3 silver-coated/impregnated connectors grew Staphylococcus aureus and Staphylococcus epidermidis. Log reduction of bacteria was not significant (range, +0.19 to -1.82). There was substantial bacterial recovery from all 3 connectors (mean ranges, 2.09 × 10 7 to 4.00 × 108) indicating that, once blood comes in contact with silver-coated/impregnated needleless connectors, their antibacterial activity is significantly reduced.
- Bloodstream infections
- Central line-associated bloodstream infections
ASJC Scopus subject areas
- Infectious Diseases
- Public Health, Environmental and Occupational Health
- Health Policy