In vivo confocal reflectance microscopy of congenital melanocytic nevi

Pantea Hashemi, Ashfaq A. Marghoob, Harold S. Rabinovitz, Alon Scope

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


The presence of congenital melanocytic nevi (CMN) is determined in utero. CMN are neural crest-derived malformations, composed mainly of a benign proliferation of melanocytes. The most common method for the classification of CMN is based upon nevus size. Small CMN are defined as smaller than 1.5 cm in diameter, medium-sized CMN are 1.5–19.9 cm, large CMN are over 20 cm in diameter, and very large (i.e., giant CMN) are over 50 cm in diameter. Rational for the size-based classification is that there is an increased risk of developing melanoma, a larger cosmetic impact and a greater surgical complexity with increasing size of CMN. In addition, large and giant CMN are often intermixed with various other neural crest-derived elements such as neural tissue and may be associated with extra-cutaneous malformations such as neurocutaneous melanocytosis, dandy-walker malformation, and vascular anomalies [1].

Original languageEnglish (US)
Title of host publicationReflectance Confocal Microscopy for Skin Diseases
PublisherSpringer Berlin Heidelberg
Number of pages17
ISBN (Electronic)9783642219979
ISBN (Print)9783642219962
StatePublished - Jan 1 2012
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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