In vivo effects of fluoride on enamel permeability

Stefano Chersoni, Angelica Bertacci, David Henry Pashley, Franklin Chi Meng Tay, Lucio Montebugnoli, Carlo Prati

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

This in vivo study evaluated the effects of topical fluoride application on enamel by repeated scanning electron microscopy analysis of replicas. Baseline fluid droplets were employed as qualitative indication of enamel permeability. CaF 2-like globules were detected in vivo after fluoride application and were not found after professional brushing, ultrasound action, or chemical extraction. Absence of water permeability of enamel was demonstrated even after removal of CaF 2-like globules. Droplets reappeared within 1 h in sodium fluoride-treated teeth, but they did not reappear even after 1 week following topical enamel treatment with acidulated phosphate fluoride. Teeth treated with an acidulate fluoride-free solution showed lack of CaF 2-like globules and no droplets for at least 1 week as detected in acidulate phosphate fluoride-treated teeth. The caries-preventing action of fluoride may be due to its ability to decrease permeability and diffusion pathways. CaF 2-like globules seem to be indirectly involved in enamel protection over time maintaining an impermeable barrier, and phosphoric acid seemed to play an unexpected fluoride-independent preventive role.

Original languageEnglish (US)
Pages (from-to)443-449
Number of pages7
JournalClinical Oral Investigations
Volume15
Issue number4
DOIs
StatePublished - Aug 1 2011

Fingerprint

Dental Enamel
Fluorides
Permeability
Tooth
Acidulated Phosphate Fluoride
Topical Fluorides
Pharmacologic Actions
Sodium Fluoride
Electron Scanning Microscopy
Phosphates
Water

Keywords

  • APF
  • CaF -like globules
  • Enamel permeability
  • NaF
  • Phosphoric acid

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Chersoni, S., Bertacci, A., Pashley, D. H., Tay, F. C. M., Montebugnoli, L., & Prati, C. (2011). In vivo effects of fluoride on enamel permeability. Clinical Oral Investigations, 15(4), 443-449. https://doi.org/10.1007/s00784-010-0406-x

In vivo effects of fluoride on enamel permeability. / Chersoni, Stefano; Bertacci, Angelica; Pashley, David Henry; Tay, Franklin Chi Meng; Montebugnoli, Lucio; Prati, Carlo.

In: Clinical Oral Investigations, Vol. 15, No. 4, 01.08.2011, p. 443-449.

Research output: Contribution to journalArticle

Chersoni, S, Bertacci, A, Pashley, DH, Tay, FCM, Montebugnoli, L & Prati, C 2011, 'In vivo effects of fluoride on enamel permeability', Clinical Oral Investigations, vol. 15, no. 4, pp. 443-449. https://doi.org/10.1007/s00784-010-0406-x
Chersoni S, Bertacci A, Pashley DH, Tay FCM, Montebugnoli L, Prati C. In vivo effects of fluoride on enamel permeability. Clinical Oral Investigations. 2011 Aug 1;15(4):443-449. https://doi.org/10.1007/s00784-010-0406-x
Chersoni, Stefano ; Bertacci, Angelica ; Pashley, David Henry ; Tay, Franklin Chi Meng ; Montebugnoli, Lucio ; Prati, Carlo. / In vivo effects of fluoride on enamel permeability. In: Clinical Oral Investigations. 2011 ; Vol. 15, No. 4. pp. 443-449.
@article{a53b0fc82b614b31ba1962bcb83689e9,
title = "In vivo effects of fluoride on enamel permeability",
abstract = "This in vivo study evaluated the effects of topical fluoride application on enamel by repeated scanning electron microscopy analysis of replicas. Baseline fluid droplets were employed as qualitative indication of enamel permeability. CaF 2-like globules were detected in vivo after fluoride application and were not found after professional brushing, ultrasound action, or chemical extraction. Absence of water permeability of enamel was demonstrated even after removal of CaF 2-like globules. Droplets reappeared within 1 h in sodium fluoride-treated teeth, but they did not reappear even after 1 week following topical enamel treatment with acidulated phosphate fluoride. Teeth treated with an acidulate fluoride-free solution showed lack of CaF 2-like globules and no droplets for at least 1 week as detected in acidulate phosphate fluoride-treated teeth. The caries-preventing action of fluoride may be due to its ability to decrease permeability and diffusion pathways. CaF 2-like globules seem to be indirectly involved in enamel protection over time maintaining an impermeable barrier, and phosphoric acid seemed to play an unexpected fluoride-independent preventive role.",
keywords = "APF, CaF -like globules, Enamel permeability, NaF, Phosphoric acid",
author = "Stefano Chersoni and Angelica Bertacci and Pashley, {David Henry} and Tay, {Franklin Chi Meng} and Lucio Montebugnoli and Carlo Prati",
year = "2011",
month = "8",
day = "1",
doi = "10.1007/s00784-010-0406-x",
language = "English (US)",
volume = "15",
pages = "443--449",
journal = "Clinical Oral Investigations",
issn = "1432-6981",
publisher = "Springer Verlag",
number = "4",

}

TY - JOUR

T1 - In vivo effects of fluoride on enamel permeability

AU - Chersoni, Stefano

AU - Bertacci, Angelica

AU - Pashley, David Henry

AU - Tay, Franklin Chi Meng

AU - Montebugnoli, Lucio

AU - Prati, Carlo

PY - 2011/8/1

Y1 - 2011/8/1

N2 - This in vivo study evaluated the effects of topical fluoride application on enamel by repeated scanning electron microscopy analysis of replicas. Baseline fluid droplets were employed as qualitative indication of enamel permeability. CaF 2-like globules were detected in vivo after fluoride application and were not found after professional brushing, ultrasound action, or chemical extraction. Absence of water permeability of enamel was demonstrated even after removal of CaF 2-like globules. Droplets reappeared within 1 h in sodium fluoride-treated teeth, but they did not reappear even after 1 week following topical enamel treatment with acidulated phosphate fluoride. Teeth treated with an acidulate fluoride-free solution showed lack of CaF 2-like globules and no droplets for at least 1 week as detected in acidulate phosphate fluoride-treated teeth. The caries-preventing action of fluoride may be due to its ability to decrease permeability and diffusion pathways. CaF 2-like globules seem to be indirectly involved in enamel protection over time maintaining an impermeable barrier, and phosphoric acid seemed to play an unexpected fluoride-independent preventive role.

AB - This in vivo study evaluated the effects of topical fluoride application on enamel by repeated scanning electron microscopy analysis of replicas. Baseline fluid droplets were employed as qualitative indication of enamel permeability. CaF 2-like globules were detected in vivo after fluoride application and were not found after professional brushing, ultrasound action, or chemical extraction. Absence of water permeability of enamel was demonstrated even after removal of CaF 2-like globules. Droplets reappeared within 1 h in sodium fluoride-treated teeth, but they did not reappear even after 1 week following topical enamel treatment with acidulated phosphate fluoride. Teeth treated with an acidulate fluoride-free solution showed lack of CaF 2-like globules and no droplets for at least 1 week as detected in acidulate phosphate fluoride-treated teeth. The caries-preventing action of fluoride may be due to its ability to decrease permeability and diffusion pathways. CaF 2-like globules seem to be indirectly involved in enamel protection over time maintaining an impermeable barrier, and phosphoric acid seemed to play an unexpected fluoride-independent preventive role.

KW - APF

KW - CaF -like globules

KW - Enamel permeability

KW - NaF

KW - Phosphoric acid

UR - http://www.scopus.com/inward/record.url?scp=79960148746&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79960148746&partnerID=8YFLogxK

U2 - 10.1007/s00784-010-0406-x

DO - 10.1007/s00784-010-0406-x

M3 - Article

VL - 15

SP - 443

EP - 449

JO - Clinical Oral Investigations

JF - Clinical Oral Investigations

SN - 1432-6981

IS - 4

ER -