Incorporation and visualization of azido-functionalized: N -oleoyl serinol in Jurkat cells, mouse brain astrocytes, 3T3 fibroblasts and human brain microvascular endothelial cells

T. Walter, L. Collenburg, L. Japtok, B. Kleuser, S. Schneider-Schaulies, N. Müller, J. Becam, A. Schubert-Unkmeir, J. N. Kong, Erhard Bieberich, J. Seibel

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The synthesis and biological evaluation of azido-N-oleoyl serinol is reported. It mimicks biofunctional lipid ceramides and has shown to be capable of click reactions for cell membrane imaging in Jurkat and human brain microvascular endothelial cells.

Original languageEnglish (US)
Pages (from-to)8612-8614
Number of pages3
JournalChemical Communications
Volume52
Issue number55
DOIs
StatePublished - Jan 1 2016

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Ceramides
Endothelial cells
Fibroblasts
Cell membranes
Lipids
Brain
Visualization
Imaging techniques
Astrocytes
N-oleoylserinol

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Incorporation and visualization of azido-functionalized : N -oleoyl serinol in Jurkat cells, mouse brain astrocytes, 3T3 fibroblasts and human brain microvascular endothelial cells. / Walter, T.; Collenburg, L.; Japtok, L.; Kleuser, B.; Schneider-Schaulies, S.; Müller, N.; Becam, J.; Schubert-Unkmeir, A.; Kong, J. N.; Bieberich, Erhard; Seibel, J.

In: Chemical Communications, Vol. 52, No. 55, 01.01.2016, p. 8612-8614.

Research output: Contribution to journalArticle

Walter, T, Collenburg, L, Japtok, L, Kleuser, B, Schneider-Schaulies, S, Müller, N, Becam, J, Schubert-Unkmeir, A, Kong, JN, Bieberich, E & Seibel, J 2016, 'Incorporation and visualization of azido-functionalized: N -oleoyl serinol in Jurkat cells, mouse brain astrocytes, 3T3 fibroblasts and human brain microvascular endothelial cells', Chemical Communications, vol. 52, no. 55, pp. 8612-8614. https://doi.org/10.1039/c6cc02879a
Walter, T. ; Collenburg, L. ; Japtok, L. ; Kleuser, B. ; Schneider-Schaulies, S. ; Müller, N. ; Becam, J. ; Schubert-Unkmeir, A. ; Kong, J. N. ; Bieberich, Erhard ; Seibel, J. / Incorporation and visualization of azido-functionalized : N -oleoyl serinol in Jurkat cells, mouse brain astrocytes, 3T3 fibroblasts and human brain microvascular endothelial cells. In: Chemical Communications. 2016 ; Vol. 52, No. 55. pp. 8612-8614.
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