TY - JOUR
T1 - Induced premaxillary suture fusion
T2 - Class III malocclusion model
AU - Ruan, W. H.
AU - Winger, J. N.
AU - Yu, J. C.
AU - Borke, J. L.
PY - 2008/9
Y1 - 2008/9
N2 - The etiology of class III malocclusion remains unknown. The present study investigates the relationship between craniofacial morphology and premaxillary suture fusion to test the hypothesis that class III malocclusion may be related to premaxillary suture fusion, Cyanoacrylate was applied to immobilize the left premaxillary suture in the experimental group. Sham surgeries in rats were used for controls. Dental impressions and radiographs were taken before and after surgery for comparison of craniofacial differences between groups. Overall cranial base lengths, craniofacial widths, and craniofacial angulations related to the anterior base showed significant differences between groups. At the end of the experiment, the growth of the snout in the experimental group was inhibited and deviated to the treated side, while no obvious change was seen in the control group. The results show that induced premaxillary suture fusion can affect craniofacial morphology and indicate that premature premaxillary suture fusion may result in class III malocclusion.
AB - The etiology of class III malocclusion remains unknown. The present study investigates the relationship between craniofacial morphology and premaxillary suture fusion to test the hypothesis that class III malocclusion may be related to premaxillary suture fusion, Cyanoacrylate was applied to immobilize the left premaxillary suture in the experimental group. Sham surgeries in rats were used for controls. Dental impressions and radiographs were taken before and after surgery for comparison of craniofacial differences between groups. Overall cranial base lengths, craniofacial widths, and craniofacial angulations related to the anterior base showed significant differences between groups. At the end of the experiment, the growth of the snout in the experimental group was inhibited and deviated to the treated side, while no obvious change was seen in the control group. The results show that induced premaxillary suture fusion can affect craniofacial morphology and indicate that premature premaxillary suture fusion may result in class III malocclusion.
KW - Animal model
KW - Artificial premaxillary suture fusion
KW - Class III malocclusion
KW - Craniofacial morphology
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U2 - 10.1177/154405910808700901
DO - 10.1177/154405910808700901
M3 - Article
C2 - 18719213
AN - SCOPUS:52649091189
SN - 0022-0345
VL - 87
SP - 856
EP - 860
JO - Journal of Dental Research
JF - Journal of Dental Research
IS - 9
ER -