Induction of Tumor Necrosis Factor during Extracorporeal Blood Purification

Gerhard Lonnemann, Jos W.m. Van Der Meer, Joseph Gerard Cannon, Charles A. Dinarello, Karl M. Koch, Céline Granolleras, Gerard Deschodt, Stanley Shaldon

Research output: Contribution to journalLetter

52 Citations (Scopus)

Abstract

To the Editor: Recent studies have shown that blood monocytes become activated during regular hemodialysis and produce interleukin-1.1 2 3 Monocyte products such as interleukin-1 are thought to contribute to both the short-term and long-term changes that are observed with hemodialysis and, to a lesser extent, with hemofiltration.4 We now describe a patient who became acutely ill during a hemofiltration procedure that was associated with a markedly elevated plasma level of tumor necrosis factor. A 21-year-old woman with end-stage renal disease due to interstitial nephritis had received over 650 uneventful treatments using post-dilutional hemofiltration over the previous five years. Two weeks earlier,…

Original languageEnglish (US)
Pages (from-to)963-964
Number of pages2
JournalNew England Journal of Medicine
Volume317
Issue number15
DOIs
StatePublished - Oct 8 1987

Fingerprint

Hemofiltration
Renal Dialysis
Monocytes
Tumor Necrosis Factor-alpha
Interstitial Nephritis
Interleukin-1
Chronic Kidney Failure
Interleukin-2
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Lonnemann, G., Van Der Meer, J. W. M., Cannon, J. G., Dinarello, C. A., Koch, K. M., Granolleras, C., ... Shaldon, S. (1987). Induction of Tumor Necrosis Factor during Extracorporeal Blood Purification. New England Journal of Medicine, 317(15), 963-964. https://doi.org/10.1056/NEJM198710083171515

Induction of Tumor Necrosis Factor during Extracorporeal Blood Purification. / Lonnemann, Gerhard; Van Der Meer, Jos W.m.; Cannon, Joseph Gerard; Dinarello, Charles A.; Koch, Karl M.; Granolleras, Céline; Deschodt, Gerard; Shaldon, Stanley.

In: New England Journal of Medicine, Vol. 317, No. 15, 08.10.1987, p. 963-964.

Research output: Contribution to journalLetter

Lonnemann, G, Van Der Meer, JWM, Cannon, JG, Dinarello, CA, Koch, KM, Granolleras, C, Deschodt, G & Shaldon, S 1987, 'Induction of Tumor Necrosis Factor during Extracorporeal Blood Purification', New England Journal of Medicine, vol. 317, no. 15, pp. 963-964. https://doi.org/10.1056/NEJM198710083171515
Lonnemann G, Van Der Meer JWM, Cannon JG, Dinarello CA, Koch KM, Granolleras C et al. Induction of Tumor Necrosis Factor during Extracorporeal Blood Purification. New England Journal of Medicine. 1987 Oct 8;317(15):963-964. https://doi.org/10.1056/NEJM198710083171515
Lonnemann, Gerhard ; Van Der Meer, Jos W.m. ; Cannon, Joseph Gerard ; Dinarello, Charles A. ; Koch, Karl M. ; Granolleras, Céline ; Deschodt, Gerard ; Shaldon, Stanley. / Induction of Tumor Necrosis Factor during Extracorporeal Blood Purification. In: New England Journal of Medicine. 1987 ; Vol. 317, No. 15. pp. 963-964.
@article{4e0a5f62566f478d8f13c480e6af3523,
title = "Induction of Tumor Necrosis Factor during Extracorporeal Blood Purification",
abstract = "To the Editor: Recent studies have shown that blood monocytes become activated during regular hemodialysis and produce interleukin-1.1 2 3 Monocyte products such as interleukin-1 are thought to contribute to both the short-term and long-term changes that are observed with hemodialysis and, to a lesser extent, with hemofiltration.4 We now describe a patient who became acutely ill during a hemofiltration procedure that was associated with a markedly elevated plasma level of tumor necrosis factor. A 21-year-old woman with end-stage renal disease due to interstitial nephritis had received over 650 uneventful treatments using post-dilutional hemofiltration over the previous five years. Two weeks earlier,…",
author = "Gerhard Lonnemann and {Van Der Meer}, {Jos W.m.} and Cannon, {Joseph Gerard} and Dinarello, {Charles A.} and Koch, {Karl M.} and C{\'e}line Granolleras and Gerard Deschodt and Stanley Shaldon",
year = "1987",
month = "10",
day = "8",
doi = "10.1056/NEJM198710083171515",
language = "English (US)",
volume = "317",
pages = "963--964",
journal = "New England Journal of Medicine",
issn = "0028-4793",
publisher = "Massachussetts Medical Society",
number = "15",

}

TY - JOUR

T1 - Induction of Tumor Necrosis Factor during Extracorporeal Blood Purification

AU - Lonnemann, Gerhard

AU - Van Der Meer, Jos W.m.

AU - Cannon, Joseph Gerard

AU - Dinarello, Charles A.

AU - Koch, Karl M.

AU - Granolleras, Céline

AU - Deschodt, Gerard

AU - Shaldon, Stanley

PY - 1987/10/8

Y1 - 1987/10/8

N2 - To the Editor: Recent studies have shown that blood monocytes become activated during regular hemodialysis and produce interleukin-1.1 2 3 Monocyte products such as interleukin-1 are thought to contribute to both the short-term and long-term changes that are observed with hemodialysis and, to a lesser extent, with hemofiltration.4 We now describe a patient who became acutely ill during a hemofiltration procedure that was associated with a markedly elevated plasma level of tumor necrosis factor. A 21-year-old woman with end-stage renal disease due to interstitial nephritis had received over 650 uneventful treatments using post-dilutional hemofiltration over the previous five years. Two weeks earlier,…

AB - To the Editor: Recent studies have shown that blood monocytes become activated during regular hemodialysis and produce interleukin-1.1 2 3 Monocyte products such as interleukin-1 are thought to contribute to both the short-term and long-term changes that are observed with hemodialysis and, to a lesser extent, with hemofiltration.4 We now describe a patient who became acutely ill during a hemofiltration procedure that was associated with a markedly elevated plasma level of tumor necrosis factor. A 21-year-old woman with end-stage renal disease due to interstitial nephritis had received over 650 uneventful treatments using post-dilutional hemofiltration over the previous five years. Two weeks earlier,…

UR - http://www.scopus.com/inward/record.url?scp=0023242423&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023242423&partnerID=8YFLogxK

U2 - 10.1056/NEJM198710083171515

DO - 10.1056/NEJM198710083171515

M3 - Letter

C2 - 3627217

AN - SCOPUS:0023242423

VL - 317

SP - 963

EP - 964

JO - New England Journal of Medicine

JF - New England Journal of Medicine

SN - 0028-4793

IS - 15

ER -