TY - JOUR
T1 - Induction of Tumor Necrosis Factor during Extracorporeal Blood Purification
AU - Lonnemann, Gerhard
AU - Van Der Meer, Jos W.m.
AU - Cannon, Joseph G.
AU - Dinarello, Charles A.
AU - Koch, Karl M.
AU - Granolleras, Céline
AU - Deschodt, Gerard
AU - Shaldon, Stanley
PY - 1987/10/8
Y1 - 1987/10/8
N2 - To the Editor: Recent studies have shown that blood monocytes become activated during regular hemodialysis and produce interleukin-1.1 2 3 Monocyte products such as interleukin-1 are thought to contribute to both the short-term and long-term changes that are observed with hemodialysis and, to a lesser extent, with hemofiltration.4 We now describe a patient who became acutely ill during a hemofiltration procedure that was associated with a markedly elevated plasma level of tumor necrosis factor. A 21-year-old woman with end-stage renal disease due to interstitial nephritis had received over 650 uneventful treatments using post-dilutional hemofiltration over the previous five years. Two weeks earlier,…
AB - To the Editor: Recent studies have shown that blood monocytes become activated during regular hemodialysis and produce interleukin-1.1 2 3 Monocyte products such as interleukin-1 are thought to contribute to both the short-term and long-term changes that are observed with hemodialysis and, to a lesser extent, with hemofiltration.4 We now describe a patient who became acutely ill during a hemofiltration procedure that was associated with a markedly elevated plasma level of tumor necrosis factor. A 21-year-old woman with end-stage renal disease due to interstitial nephritis had received over 650 uneventful treatments using post-dilutional hemofiltration over the previous five years. Two weeks earlier,…
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U2 - 10.1056/NEJM198710083171515
DO - 10.1056/NEJM198710083171515
M3 - Letter
C2 - 3627217
AN - SCOPUS:0023242423
SN - 0028-4793
VL - 317
SP - 963
EP - 964
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 15
ER -