Abstract
Organisms conforming to "rhodochrous taxon" were isolated from three immunocompromised patients, suggesting a pathogenic role for the organisms. The organisms are partially acid-fast, grampositive catalase positive rods which form orange or red colonies aerobically in three or four days on Sabouraud, Mueller-Hinton and Middlebrook 7H-10 agars. They are differentiated from Nocardia by morphology and ability to degrade ethylene glycol in 7H-10 media. Two of these clinical isolates and a reference strain were injected intraperitoneally into guinea pigs, half of which received methylprednisolone intramuscularly beginning three days prior to inoculation. Steroid-treated animals exhibited clinical illness, diffuse peritonitis and recovery of inoculated organisms whereas one of three nonsteroid-treated animals exhibited a localized abscess without recovery of organisms. This study suggests that rhodochrous may be pathogenic under conditions of immune compromise.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 298-302 |
| Number of pages | 5 |
| Journal | The American Journal of Medicine |
| Volume | 65 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 1 1978 |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Infections caused by rhodochrous. / Haburchak, David R; Jeffery, Betty; Higbee, James W.; Everett, E. Dale.
In: The American Journal of Medicine, Vol. 65, No. 2, 01.01.1978, p. 298-302.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Infections caused by rhodochrous
AU - Haburchak, David R
AU - Jeffery, Betty
AU - Higbee, James W.
AU - Everett, E. Dale
PY - 1978/1/1
Y1 - 1978/1/1
N2 - Organisms conforming to "rhodochrous taxon" were isolated from three immunocompromised patients, suggesting a pathogenic role for the organisms. The organisms are partially acid-fast, grampositive catalase positive rods which form orange or red colonies aerobically in three or four days on Sabouraud, Mueller-Hinton and Middlebrook 7H-10 agars. They are differentiated from Nocardia by morphology and ability to degrade ethylene glycol in 7H-10 media. Two of these clinical isolates and a reference strain were injected intraperitoneally into guinea pigs, half of which received methylprednisolone intramuscularly beginning three days prior to inoculation. Steroid-treated animals exhibited clinical illness, diffuse peritonitis and recovery of inoculated organisms whereas one of three nonsteroid-treated animals exhibited a localized abscess without recovery of organisms. This study suggests that rhodochrous may be pathogenic under conditions of immune compromise.
AB - Organisms conforming to "rhodochrous taxon" were isolated from three immunocompromised patients, suggesting a pathogenic role for the organisms. The organisms are partially acid-fast, grampositive catalase positive rods which form orange or red colonies aerobically in three or four days on Sabouraud, Mueller-Hinton and Middlebrook 7H-10 agars. They are differentiated from Nocardia by morphology and ability to degrade ethylene glycol in 7H-10 media. Two of these clinical isolates and a reference strain were injected intraperitoneally into guinea pigs, half of which received methylprednisolone intramuscularly beginning three days prior to inoculation. Steroid-treated animals exhibited clinical illness, diffuse peritonitis and recovery of inoculated organisms whereas one of three nonsteroid-treated animals exhibited a localized abscess without recovery of organisms. This study suggests that rhodochrous may be pathogenic under conditions of immune compromise.
UR - http://www.scopus.com/inward/record.url?scp=0017808546&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017808546&partnerID=8YFLogxK
U2 - 10.1016/0002-9343(78)90823-9
DO - 10.1016/0002-9343(78)90823-9
M3 - Article
C2 - 686014
AN - SCOPUS:0017808546
VL - 65
SP - 298
EP - 302
JO - American Journal of Medicine
JF - American Journal of Medicine
SN - 0002-9343
IS - 2
ER -