Innovative cancer treatments that augment radiotherapy or chemotherapy by the use of immunotherapy or gene therapy

Rudolf Lucas, Yona Keisari

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

Cancer is a complex multifactorial disease requiring combinations of several therapeutic modalities to treat it effectively. Despite advances in the field of prevention and treatment of cancer, morbidity and mortality remain high, especially for tumors that cannot be completely removed, as well as for those that are highly recurrent or highly metastatic. Surgery, radiotherapy and chemotherapy, alone or in combination, are currently the prevalent treatment modalities. Yet, in order to treat metastases more effectively, the immune response must be recruited. In this review, we will focus on recent patents in the field of cancer that have concentrated on combining chemotherapy or radiotherapy strategies with immunotherapy, in order to eradicate the primary tumor as well as its metastases.

Original languageEnglish (US)
Pages (from-to)201-208
Number of pages8
JournalRecent Patents on Anti-Cancer Drug Discovery
Volume1
Issue number2
DOIs
Publication statusPublished - Dec 1 2006
Externally publishedYes

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Keywords

  • Cancer
  • Chemotherapy
  • Combination therapy
  • Immunotherapy
  • Radiotherapy
  • Synergy

ASJC Scopus subject areas

  • Oncology
  • Drug Discovery
  • Cancer Research
  • Pharmacology (medical)

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