International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Richard R. Orlandi, Todd T. Kingdom, Peter H. Hwang, Timothy L. Smith, Jeremiah A. Alt, Fuad M. Baroody, Pete S. Batra, Manuel Bernal-Sprekelsen, Neil Bhattacharyya, Rakesh K. Chandra, Alexander Chiu, Martin J. Citardi, Noam A. Cohen, John Delgaudio, Martin Desrosiers, Hun Jong Dhong, Richard Douglas, Berrylin Ferguson, Wytske J. Fokkens, Christos GeorgalasAndrew Goldberg, Jan Gosepath, Daniel L. Hamilos, Joseph K. Han, Richard Harvey, Peter Hellings, Claire Hopkins, Roger Jankowski, Amin R. Javer, Robert Kern, Stilianos Kountakis, Marek L. Kowalski, Andrew Lane, Donald C. Lanza, Richard Lebowitz, Heung Man Lee, Sandra Y. Lin, Valerie Lund, Amber Luong, Wolf Mann, Bradley F. Marple, Kevin C. Mcmains, Ralph Metson, Robert Naclerio, Jayakar V. Nayak, Nobuyoshi Otori, James N. Palmer, Sanjay R. Parikh, Desiderio Passali, Anju Peters, Jay Piccirillo, David M. Poetker, Alkis J. Psaltis, Hassan H. Ramadan, Vijay R. Ramakrishnan, Herbert Riechelmann, Hwan Jung Roh, Luke Rudmik, Raymond Sacks, Rodney J. Schlosser, Brent A. Senior, Raj Sindwani, James A. Stankiewicz, Michael Stewart, Bruce K. Tan, Elina Toskala, Richard Voegels, De Yun Wang, Erik K. Weitzel, Sarah Wise, Bradford A. Woodworth, Peter John Wormald, Erin D. Wright, Bing Zhou, David W. Kennedy

Research output: Contribution to journalArticle

263 Citations (Scopus)

Abstract

Background: The body of knowledge regarding rhinosinusitis (RS) continues to expand, with rapid growth in number of publications, yet substantial variability in the quality of those presentations. In an effort to both consolidate and critically appraise this information, rhinologic experts from around the world have produced the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR:RS). Methods: Evidence-based reviews with recommendations (EBRRs) were developed for scores of topics, using previously reported methodology. Where existing evidence was insufficient for an EBRR, an evidence-based review (EBR) was produced. The sections were then synthesized and the entire manuscript was then reviewed by all authors for consensus. Results: The resulting ICAR:RS document addresses multiple topics in RS, including acute RS (ARS), chronic RS (CRS) with and without nasal polyps (CRSwNP and CRSsNP), recurrent acute RS (RARS), acute exacerbation of CRS (AECRS), and pediatric RS. Conclusion: As a critical review of the RS literature, ICAR:RS provides a thorough review of pathophysiology and evidence-based recommendations for medical and surgical treatment. It also demonstrates the significant gaps in our understanding of the pathophysiology and optimal management of RS. Too often the foundation upon which these recommendations are based is comprised of lower-level evidence. It is our hope that this summary of the evidence in RS will point out where additional research efforts may be directed.

Original languageEnglish (US)
Pages (from-to)S22-S209
JournalInternational Forum of Allergy and Rhinology
Volume6
DOIs
StatePublished - Feb 1 2016

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Keywords

  • Acute rhinosinusitis
  • Chronic rhinosinusitis
  • Endoscopic sinus surgery
  • Evidence-based medicine
  • Recurrent acute rhinosinusitis
  • Rhinosinusitis
  • Systematic review

ASJC Scopus subject areas

  • Immunology and Allergy
  • Otorhinolaryngology

Cite this

Orlandi, R. R., Kingdom, T. T., Hwang, P. H., Smith, T. L., Alt, J. A., Baroody, F. M., ... Kennedy, D. W. (2016). International Consensus Statement on Allergy and Rhinology: Rhinosinusitis. International Forum of Allergy and Rhinology, 6, S22-S209. https://doi.org/10.1002/alr.21695

International Consensus Statement on Allergy and Rhinology : Rhinosinusitis. / Orlandi, Richard R.; Kingdom, Todd T.; Hwang, Peter H.; Smith, Timothy L.; Alt, Jeremiah A.; Baroody, Fuad M.; Batra, Pete S.; Bernal-Sprekelsen, Manuel; Bhattacharyya, Neil; Chandra, Rakesh K.; Chiu, Alexander; Citardi, Martin J.; Cohen, Noam A.; Delgaudio, John; Desrosiers, Martin; Dhong, Hun Jong; Douglas, Richard; Ferguson, Berrylin; Fokkens, Wytske J.; Georgalas, Christos; Goldberg, Andrew; Gosepath, Jan; Hamilos, Daniel L.; Han, Joseph K.; Harvey, Richard; Hellings, Peter; Hopkins, Claire; Jankowski, Roger; Javer, Amin R.; Kern, Robert; Kountakis, Stilianos; Kowalski, Marek L.; Lane, Andrew; Lanza, Donald C.; Lebowitz, Richard; Lee, Heung Man; Lin, Sandra Y.; Lund, Valerie; Luong, Amber; Mann, Wolf; Marple, Bradley F.; Mcmains, Kevin C.; Metson, Ralph; Naclerio, Robert; Nayak, Jayakar V.; Otori, Nobuyoshi; Palmer, James N.; Parikh, Sanjay R.; Passali, Desiderio; Peters, Anju; Piccirillo, Jay; Poetker, David M.; Psaltis, Alkis J.; Ramadan, Hassan H.; Ramakrishnan, Vijay R.; Riechelmann, Herbert; Roh, Hwan Jung; Rudmik, Luke; Sacks, Raymond; Schlosser, Rodney J.; Senior, Brent A.; Sindwani, Raj; Stankiewicz, James A.; Stewart, Michael; Tan, Bruce K.; Toskala, Elina; Voegels, Richard; Wang, De Yun; Weitzel, Erik K.; Wise, Sarah; Woodworth, Bradford A.; Wormald, Peter John; Wright, Erin D.; Zhou, Bing; Kennedy, David W.

In: International Forum of Allergy and Rhinology, Vol. 6, 01.02.2016, p. S22-S209.

Research output: Contribution to journalArticle

Orlandi, RR, Kingdom, TT, Hwang, PH, Smith, TL, Alt, JA, Baroody, FM, Batra, PS, Bernal-Sprekelsen, M, Bhattacharyya, N, Chandra, RK, Chiu, A, Citardi, MJ, Cohen, NA, Delgaudio, J, Desrosiers, M, Dhong, HJ, Douglas, R, Ferguson, B, Fokkens, WJ, Georgalas, C, Goldberg, A, Gosepath, J, Hamilos, DL, Han, JK, Harvey, R, Hellings, P, Hopkins, C, Jankowski, R, Javer, AR, Kern, R, Kountakis, S, Kowalski, ML, Lane, A, Lanza, DC, Lebowitz, R, Lee, HM, Lin, SY, Lund, V, Luong, A, Mann, W, Marple, BF, Mcmains, KC, Metson, R, Naclerio, R, Nayak, JV, Otori, N, Palmer, JN, Parikh, SR, Passali, D, Peters, A, Piccirillo, J, Poetker, DM, Psaltis, AJ, Ramadan, HH, Ramakrishnan, VR, Riechelmann, H, Roh, HJ, Rudmik, L, Sacks, R, Schlosser, RJ, Senior, BA, Sindwani, R, Stankiewicz, JA, Stewart, M, Tan, BK, Toskala, E, Voegels, R, Wang, DY, Weitzel, EK, Wise, S, Woodworth, BA, Wormald, PJ, Wright, ED, Zhou, B & Kennedy, DW 2016, 'International Consensus Statement on Allergy and Rhinology: Rhinosinusitis', International Forum of Allergy and Rhinology, vol. 6, pp. S22-S209. https://doi.org/10.1002/alr.21695
Orlandi, Richard R. ; Kingdom, Todd T. ; Hwang, Peter H. ; Smith, Timothy L. ; Alt, Jeremiah A. ; Baroody, Fuad M. ; Batra, Pete S. ; Bernal-Sprekelsen, Manuel ; Bhattacharyya, Neil ; Chandra, Rakesh K. ; Chiu, Alexander ; Citardi, Martin J. ; Cohen, Noam A. ; Delgaudio, John ; Desrosiers, Martin ; Dhong, Hun Jong ; Douglas, Richard ; Ferguson, Berrylin ; Fokkens, Wytske J. ; Georgalas, Christos ; Goldberg, Andrew ; Gosepath, Jan ; Hamilos, Daniel L. ; Han, Joseph K. ; Harvey, Richard ; Hellings, Peter ; Hopkins, Claire ; Jankowski, Roger ; Javer, Amin R. ; Kern, Robert ; Kountakis, Stilianos ; Kowalski, Marek L. ; Lane, Andrew ; Lanza, Donald C. ; Lebowitz, Richard ; Lee, Heung Man ; Lin, Sandra Y. ; Lund, Valerie ; Luong, Amber ; Mann, Wolf ; Marple, Bradley F. ; Mcmains, Kevin C. ; Metson, Ralph ; Naclerio, Robert ; Nayak, Jayakar V. ; Otori, Nobuyoshi ; Palmer, James N. ; Parikh, Sanjay R. ; Passali, Desiderio ; Peters, Anju ; Piccirillo, Jay ; Poetker, David M. ; Psaltis, Alkis J. ; Ramadan, Hassan H. ; Ramakrishnan, Vijay R. ; Riechelmann, Herbert ; Roh, Hwan Jung ; Rudmik, Luke ; Sacks, Raymond ; Schlosser, Rodney J. ; Senior, Brent A. ; Sindwani, Raj ; Stankiewicz, James A. ; Stewart, Michael ; Tan, Bruce K. ; Toskala, Elina ; Voegels, Richard ; Wang, De Yun ; Weitzel, Erik K. ; Wise, Sarah ; Woodworth, Bradford A. ; Wormald, Peter John ; Wright, Erin D. ; Zhou, Bing ; Kennedy, David W. / International Consensus Statement on Allergy and Rhinology : Rhinosinusitis. In: International Forum of Allergy and Rhinology. 2016 ; Vol. 6. pp. S22-S209.
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title = "International Consensus Statement on Allergy and Rhinology: Rhinosinusitis",
abstract = "Background: The body of knowledge regarding rhinosinusitis (RS) continues to expand, with rapid growth in number of publications, yet substantial variability in the quality of those presentations. In an effort to both consolidate and critically appraise this information, rhinologic experts from around the world have produced the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR:RS). Methods: Evidence-based reviews with recommendations (EBRRs) were developed for scores of topics, using previously reported methodology. Where existing evidence was insufficient for an EBRR, an evidence-based review (EBR) was produced. The sections were then synthesized and the entire manuscript was then reviewed by all authors for consensus. Results: The resulting ICAR:RS document addresses multiple topics in RS, including acute RS (ARS), chronic RS (CRS) with and without nasal polyps (CRSwNP and CRSsNP), recurrent acute RS (RARS), acute exacerbation of CRS (AECRS), and pediatric RS. Conclusion: As a critical review of the RS literature, ICAR:RS provides a thorough review of pathophysiology and evidence-based recommendations for medical and surgical treatment. It also demonstrates the significant gaps in our understanding of the pathophysiology and optimal management of RS. Too often the foundation upon which these recommendations are based is comprised of lower-level evidence. It is our hope that this summary of the evidence in RS will point out where additional research efforts may be directed.",
keywords = "Acute rhinosinusitis, Chronic rhinosinusitis, Endoscopic sinus surgery, Evidence-based medicine, Recurrent acute rhinosinusitis, Rhinosinusitis, Systematic review",
author = "Orlandi, {Richard R.} and Kingdom, {Todd T.} and Hwang, {Peter H.} and Smith, {Timothy L.} and Alt, {Jeremiah A.} and Baroody, {Fuad M.} and Batra, {Pete S.} and Manuel Bernal-Sprekelsen and Neil Bhattacharyya and Chandra, {Rakesh K.} and Alexander Chiu and Citardi, {Martin J.} and Cohen, {Noam A.} and John Delgaudio and Martin Desrosiers and Dhong, {Hun Jong} and Richard Douglas and Berrylin Ferguson and Fokkens, {Wytske J.} and Christos Georgalas and Andrew Goldberg and Jan Gosepath and Hamilos, {Daniel L.} and Han, {Joseph K.} and Richard Harvey and Peter Hellings and Claire Hopkins and Roger Jankowski and Javer, {Amin R.} and Robert Kern and Stilianos Kountakis and Kowalski, {Marek L.} and Andrew Lane and Lanza, {Donald C.} and Richard Lebowitz and Lee, {Heung Man} and Lin, {Sandra Y.} and Valerie Lund and Amber Luong and Wolf Mann and Marple, {Bradley F.} and Mcmains, {Kevin C.} and Ralph Metson and Robert Naclerio and Nayak, {Jayakar V.} and Nobuyoshi Otori and Palmer, {James N.} and Parikh, {Sanjay R.} and Desiderio Passali and Anju Peters and Jay Piccirillo and Poetker, {David M.} and Psaltis, {Alkis J.} and Ramadan, {Hassan H.} and Ramakrishnan, {Vijay R.} and Herbert Riechelmann and Roh, {Hwan Jung} and Luke Rudmik and Raymond Sacks and Schlosser, {Rodney J.} and Senior, {Brent A.} and Raj Sindwani and Stankiewicz, {James A.} and Michael Stewart and Tan, {Bruce K.} and Elina Toskala and Richard Voegels and Wang, {De Yun} and Weitzel, {Erik K.} and Sarah Wise and Woodworth, {Bradford A.} and Wormald, {Peter John} and Wright, {Erin D.} and Bing Zhou and Kennedy, {David W.}",
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TY - JOUR

T1 - International Consensus Statement on Allergy and Rhinology

T2 - Rhinosinusitis

AU - Orlandi, Richard R.

AU - Kingdom, Todd T.

AU - Hwang, Peter H.

AU - Smith, Timothy L.

AU - Alt, Jeremiah A.

AU - Baroody, Fuad M.

AU - Batra, Pete S.

AU - Bernal-Sprekelsen, Manuel

AU - Bhattacharyya, Neil

AU - Chandra, Rakesh K.

AU - Chiu, Alexander

AU - Citardi, Martin J.

AU - Cohen, Noam A.

AU - Delgaudio, John

AU - Desrosiers, Martin

AU - Dhong, Hun Jong

AU - Douglas, Richard

AU - Ferguson, Berrylin

AU - Fokkens, Wytske J.

AU - Georgalas, Christos

AU - Goldberg, Andrew

AU - Gosepath, Jan

AU - Hamilos, Daniel L.

AU - Han, Joseph K.

AU - Harvey, Richard

AU - Hellings, Peter

AU - Hopkins, Claire

AU - Jankowski, Roger

AU - Javer, Amin R.

AU - Kern, Robert

AU - Kountakis, Stilianos

AU - Kowalski, Marek L.

AU - Lane, Andrew

AU - Lanza, Donald C.

AU - Lebowitz, Richard

AU - Lee, Heung Man

AU - Lin, Sandra Y.

AU - Lund, Valerie

AU - Luong, Amber

AU - Mann, Wolf

AU - Marple, Bradley F.

AU - Mcmains, Kevin C.

AU - Metson, Ralph

AU - Naclerio, Robert

AU - Nayak, Jayakar V.

AU - Otori, Nobuyoshi

AU - Palmer, James N.

AU - Parikh, Sanjay R.

AU - Passali, Desiderio

AU - Peters, Anju

AU - Piccirillo, Jay

AU - Poetker, David M.

AU - Psaltis, Alkis J.

AU - Ramadan, Hassan H.

AU - Ramakrishnan, Vijay R.

AU - Riechelmann, Herbert

AU - Roh, Hwan Jung

AU - Rudmik, Luke

AU - Sacks, Raymond

AU - Schlosser, Rodney J.

AU - Senior, Brent A.

AU - Sindwani, Raj

AU - Stankiewicz, James A.

AU - Stewart, Michael

AU - Tan, Bruce K.

AU - Toskala, Elina

AU - Voegels, Richard

AU - Wang, De Yun

AU - Weitzel, Erik K.

AU - Wise, Sarah

AU - Woodworth, Bradford A.

AU - Wormald, Peter John

AU - Wright, Erin D.

AU - Zhou, Bing

AU - Kennedy, David W.

PY - 2016/2/1

Y1 - 2016/2/1

N2 - Background: The body of knowledge regarding rhinosinusitis (RS) continues to expand, with rapid growth in number of publications, yet substantial variability in the quality of those presentations. In an effort to both consolidate and critically appraise this information, rhinologic experts from around the world have produced the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR:RS). Methods: Evidence-based reviews with recommendations (EBRRs) were developed for scores of topics, using previously reported methodology. Where existing evidence was insufficient for an EBRR, an evidence-based review (EBR) was produced. The sections were then synthesized and the entire manuscript was then reviewed by all authors for consensus. Results: The resulting ICAR:RS document addresses multiple topics in RS, including acute RS (ARS), chronic RS (CRS) with and without nasal polyps (CRSwNP and CRSsNP), recurrent acute RS (RARS), acute exacerbation of CRS (AECRS), and pediatric RS. Conclusion: As a critical review of the RS literature, ICAR:RS provides a thorough review of pathophysiology and evidence-based recommendations for medical and surgical treatment. It also demonstrates the significant gaps in our understanding of the pathophysiology and optimal management of RS. Too often the foundation upon which these recommendations are based is comprised of lower-level evidence. It is our hope that this summary of the evidence in RS will point out where additional research efforts may be directed.

AB - Background: The body of knowledge regarding rhinosinusitis (RS) continues to expand, with rapid growth in number of publications, yet substantial variability in the quality of those presentations. In an effort to both consolidate and critically appraise this information, rhinologic experts from around the world have produced the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR:RS). Methods: Evidence-based reviews with recommendations (EBRRs) were developed for scores of topics, using previously reported methodology. Where existing evidence was insufficient for an EBRR, an evidence-based review (EBR) was produced. The sections were then synthesized and the entire manuscript was then reviewed by all authors for consensus. Results: The resulting ICAR:RS document addresses multiple topics in RS, including acute RS (ARS), chronic RS (CRS) with and without nasal polyps (CRSwNP and CRSsNP), recurrent acute RS (RARS), acute exacerbation of CRS (AECRS), and pediatric RS. Conclusion: As a critical review of the RS literature, ICAR:RS provides a thorough review of pathophysiology and evidence-based recommendations for medical and surgical treatment. It also demonstrates the significant gaps in our understanding of the pathophysiology and optimal management of RS. Too often the foundation upon which these recommendations are based is comprised of lower-level evidence. It is our hope that this summary of the evidence in RS will point out where additional research efforts may be directed.

KW - Acute rhinosinusitis

KW - Chronic rhinosinusitis

KW - Endoscopic sinus surgery

KW - Evidence-based medicine

KW - Recurrent acute rhinosinusitis

KW - Rhinosinusitis

KW - Systematic review

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