Intracerebral Hemorrhage: Blood Components and Neurotoxicity

Neha Madangarli, Frederick Bonsack, Rajaneekar Dasari, Sangeetha Sukumari-Ramesh

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Intracerebral hemorrhage (ICH) is a subtype of stroke which is associated with the highest mortality and morbidity rates of all strokes. Although it is a major public health problem, there is no effective treatment for ICH. As a consequence of ICH, various blood components accumulate in the brain parenchyma and are responsible for much of the secondary brain damage and ICH-induced neurological deficits. Therefore, the strategies that could attenuate the blood component-induced neurotoxicity and improve hematoma resolution are highly needed. The present article provides an overview of blood-induced brain injury after ICH and emphasizes the need to conduct further studies elucidating the mechanisms of hematoma resolution after ICH.

Original languageEnglish (US)
JournalBrain Sciences
Volume9
Issue number11
DOIs
StatePublished - Nov 9 2019
Externally publishedYes

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