Is there a role for bedside ultrasound in malaria? A survey of the literature

Paolo Malerba, Daniel Kaminstein, Enrico Brunetti, Tommaso Manciulli

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Purpose: Point-of-care ultrasound (POCUS) has proven utility in the evaluation and treatment of many tropical diseases. Its role in malaria has been studied, but its value for the clinician at the bedside is unclear. Our review aimed at summarizing the existing studies to assess the usefulness, if any, of POCUS in treating malaria. Methods: We used Boolean operators using keywords “malaria”, “acoustic”, “ultrasound”, “echography”, and “ultrasonography” to search PubMed, Scopus, and Science Direct in three languages (Italian, French, and English). Results: We found 22 eligible references. Organs explored include the liver, spleen, heart, optic nerve sheath diameter (ONSD), kidney, lungs, and cerebral vasculature. Multiple pathologic findings by ultrasound are reported, but few demonstrate clinical utility. Current studies involve small numbers of patients, and a few trends emerge when studies are compared. The ability to combine study results is limited due to the significant heterogeneity that exists between studies in regards to both methods of evaluation and the reporting of organ pathology and malaria severity. Conclusions and assessment: A review of the current literature indicates that the use of ultrasound by clinicians adds little to the diagnostic evaluation of patients with malaria. Our review did find that measurements of the spleen, lungs, optic nerve sheath diameter, and cerebral blood flow have potential utility in specific patient populations. Further studies are needed to evaluate whether this utility persists when a larger sample size is used.

Original languageEnglish (US)
JournalJournal of Ultrasound
DOIs
StateAccepted/In press - Jan 1 2019

Fingerprint

Malaria
Point-of-Care Systems
Optic Nerve
Ultrasonography
Cerebrovascular Circulation
Spleen
Lung
Aptitude
PubMed
Acoustics
Sample Size
Language
Surveys and Questionnaires
Pathology
Kidney
Liver
Population
Therapeutics

Keywords

  • Cerebral malaria
  • Diagnosis
  • Malaria
  • Ultrasound

ASJC Scopus subject areas

  • Internal Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

Is there a role for bedside ultrasound in malaria? A survey of the literature. / Malerba, Paolo; Kaminstein, Daniel; Brunetti, Enrico; Manciulli, Tommaso.

In: Journal of Ultrasound, 01.01.2019.

Research output: Contribution to journalReview article

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