Lacrimal gland myoepithelioma in a rhesus macaque (Macaca mulatta)

John S. Munday, Nancy A. Rodriguez, Dilip Abraham Thomas

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

An 18-year-old rhesus macaque (Macaca mulatta) developed ptosis of the left upper eyelid due to a mass that had first been observed 10 years previously. The 11 × 7 × 7-mm mass was surgically excised, and the ptosis resolved after 5 days. Histologic examination of the mass revealed two confluent cell populations. Most cells were spindle-shaped and were arranged in loose fascicles. Smaller numbers of cells had squamous differentiation. The spindle-shaped cells expressed smooth muscle actin. Cells with squamous differentiation did not express smooth muscle actin, but did, along with around half of the spindle-shaped cells, express pan-cytokeratin. On the basis of histologic and immunohistochemical findings, the mass was diagnosed as myoepithelioma. The neoplasm most likely originated from the palpebral lobe of the lacrimal gland, although accessory lacrimal gland origin could not be excluded. Recurrence of the neoplasm has not been observed 6 months after surgery.

Original languageEnglish (US)
Pages (from-to)443-446
Number of pages4
JournalComparative Medicine
Volume54
Issue number4
StatePublished - Aug 1 2004

Fingerprint

Myoepithelioma
lacrimal apparatus
Lacrimal Apparatus
Macaca mulatta
Muscle
Actins
Eyelids
Accessories
Keratins
Epithelial Cells
Surgery
eyelids
Cells
cells
smooth muscle
Smooth Muscle Myocytes
actin
Smooth Muscle
Neoplasms
Cell Count

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • veterinary(all)

Cite this

Lacrimal gland myoepithelioma in a rhesus macaque (Macaca mulatta). / Munday, John S.; Rodriguez, Nancy A.; Thomas, Dilip Abraham.

In: Comparative Medicine, Vol. 54, No. 4, 01.08.2004, p. 443-446.

Research output: Contribution to journalArticle

Munday, JS, Rodriguez, NA & Thomas, DA 2004, 'Lacrimal gland myoepithelioma in a rhesus macaque (Macaca mulatta)', Comparative Medicine, vol. 54, no. 4, pp. 443-446.
Munday, John S. ; Rodriguez, Nancy A. ; Thomas, Dilip Abraham. / Lacrimal gland myoepithelioma in a rhesus macaque (Macaca mulatta). In: Comparative Medicine. 2004 ; Vol. 54, No. 4. pp. 443-446.
@article{c535e4ac47e2409184ef577ae503afe0,
title = "Lacrimal gland myoepithelioma in a rhesus macaque (Macaca mulatta)",
abstract = "An 18-year-old rhesus macaque (Macaca mulatta) developed ptosis of the left upper eyelid due to a mass that had first been observed 10 years previously. The 11 × 7 × 7-mm mass was surgically excised, and the ptosis resolved after 5 days. Histologic examination of the mass revealed two confluent cell populations. Most cells were spindle-shaped and were arranged in loose fascicles. Smaller numbers of cells had squamous differentiation. The spindle-shaped cells expressed smooth muscle actin. Cells with squamous differentiation did not express smooth muscle actin, but did, along with around half of the spindle-shaped cells, express pan-cytokeratin. On the basis of histologic and immunohistochemical findings, the mass was diagnosed as myoepithelioma. The neoplasm most likely originated from the palpebral lobe of the lacrimal gland, although accessory lacrimal gland origin could not be excluded. Recurrence of the neoplasm has not been observed 6 months after surgery.",
author = "Munday, {John S.} and Rodriguez, {Nancy A.} and Thomas, {Dilip Abraham}",
year = "2004",
month = "8",
day = "1",
language = "English (US)",
volume = "54",
pages = "443--446",
journal = "Comparative Medicine",
issn = "1532-0820",
publisher = "American Association for Laboratory Animal Science",
number = "4",

}

TY - JOUR

T1 - Lacrimal gland myoepithelioma in a rhesus macaque (Macaca mulatta)

AU - Munday, John S.

AU - Rodriguez, Nancy A.

AU - Thomas, Dilip Abraham

PY - 2004/8/1

Y1 - 2004/8/1

N2 - An 18-year-old rhesus macaque (Macaca mulatta) developed ptosis of the left upper eyelid due to a mass that had first been observed 10 years previously. The 11 × 7 × 7-mm mass was surgically excised, and the ptosis resolved after 5 days. Histologic examination of the mass revealed two confluent cell populations. Most cells were spindle-shaped and were arranged in loose fascicles. Smaller numbers of cells had squamous differentiation. The spindle-shaped cells expressed smooth muscle actin. Cells with squamous differentiation did not express smooth muscle actin, but did, along with around half of the spindle-shaped cells, express pan-cytokeratin. On the basis of histologic and immunohistochemical findings, the mass was diagnosed as myoepithelioma. The neoplasm most likely originated from the palpebral lobe of the lacrimal gland, although accessory lacrimal gland origin could not be excluded. Recurrence of the neoplasm has not been observed 6 months after surgery.

AB - An 18-year-old rhesus macaque (Macaca mulatta) developed ptosis of the left upper eyelid due to a mass that had first been observed 10 years previously. The 11 × 7 × 7-mm mass was surgically excised, and the ptosis resolved after 5 days. Histologic examination of the mass revealed two confluent cell populations. Most cells were spindle-shaped and were arranged in loose fascicles. Smaller numbers of cells had squamous differentiation. The spindle-shaped cells expressed smooth muscle actin. Cells with squamous differentiation did not express smooth muscle actin, but did, along with around half of the spindle-shaped cells, express pan-cytokeratin. On the basis of histologic and immunohistochemical findings, the mass was diagnosed as myoepithelioma. The neoplasm most likely originated from the palpebral lobe of the lacrimal gland, although accessory lacrimal gland origin could not be excluded. Recurrence of the neoplasm has not been observed 6 months after surgery.

UR - http://www.scopus.com/inward/record.url?scp=4143103959&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=4143103959&partnerID=8YFLogxK

M3 - Article

VL - 54

SP - 443

EP - 446

JO - Comparative Medicine

JF - Comparative Medicine

SN - 1532-0820

IS - 4

ER -