TY - JOUR
T1 - Laparoscopy in gynecologic surgery
T2 - Adhesion development, prevention, and use of adjunctive therapies
AU - Awonuga, Awoniyi O.
AU - Saed, Ghassan M.
AU - Diamond, Michael P.
PY - 2009/9
Y1 - 2009/9
N2 - Laparoscopic surgery has several proven advantages over open surgery. However, the role of laparoscopy in adhesion development and applicability of adhesion barrier is unclear. Adhesions occur in majority of women undergoing major laparoscopic gynecologic surgery and its sequel, are associated with significant morbidity, economic, and medico-legal consequences. Microsurgical principles and technique alone are insufficient to prevent adhesion formation. However, several biases limit the ability to compare different types of adhesion prevention products for efficacy. It is hoped that better understanding of pathways and demonstration of the mechanisms involved in adhesions formation may help in future research into this field.
AB - Laparoscopic surgery has several proven advantages over open surgery. However, the role of laparoscopy in adhesion development and applicability of adhesion barrier is unclear. Adhesions occur in majority of women undergoing major laparoscopic gynecologic surgery and its sequel, are associated with significant morbidity, economic, and medico-legal consequences. Microsurgical principles and technique alone are insufficient to prevent adhesion formation. However, several biases limit the ability to compare different types of adhesion prevention products for efficacy. It is hoped that better understanding of pathways and demonstration of the mechanisms involved in adhesions formation may help in future research into this field.
KW - Adhesion
KW - Adjunctive therapies
KW - Operative laparoscopy
UR - http://www.scopus.com/inward/record.url?scp=69449098533&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=69449098533&partnerID=8YFLogxK
U2 - 10.1097/GRF.0b013e3181b0c121
DO - 10.1097/GRF.0b013e3181b0c121
M3 - Article
C2 - 19661757
AN - SCOPUS:69449098533
SN - 0009-9201
VL - 52
SP - 412
EP - 422
JO - Clinical Obstetrics and Gynecology
JF - Clinical Obstetrics and Gynecology
IS - 3
ER -