Abstract
Breast cancer is the most commonly diagnosed cancer among women. To date, the use of efficacy randomized controlled trials (RCTs) in breast cancer have resulted in dramatic improvements in oncologic outcomes for this disease. However, not every question pertinent to breast cancer is amenable to such efficacy trials. This chapter will discuss some of the unique aspects of breast cancer that make efficacy RCTs challenging and/or impractical, how comparative effectiveness research can be used to address these issues, and identify several key questions which would benefit from ongoing comparative effectiveness research.
Original language | English (US) |
---|---|
Pages (from-to) | 15-30 |
Number of pages | 16 |
Journal | Cancer treatment and research |
Volume | 164 |
DOIs | |
State | Published - 2015 |
Externally published | Yes |
Keywords
- Axillary lymph node dissection
- Breast cancer
- Breast conserving therapy (BCT)
- Comparative effectiveness research
- Hormonal therapy
- Hormone receptor status
- Mastectomy
- Sentinel lymph node biopsy
ASJC Scopus subject areas
- Oncology
- Cancer Research