Ligations from homocysteine isopeptide via 6-membered cyclic transition states

Siva S. Panda, Alan R. Katritzky

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Efficient synthesis of S-acyl homocysteine allow chemical ligation (S-acyl to N-acyl transfer) via 6-membered cyclic transition state. The results represent the first example of successful isopeptide ligation starting from S-acyl homocysteine.

Original languageEnglish (US)
Pages (from-to)1519-1524
Number of pages6
JournalJournal of the Indian Chemical Society
Volume90
Issue number10
StatePublished - Oct 2013

Keywords

  • Homocysteine isopeptide
  • Ligation
  • Microwave
  • S to N-acyl migration

ASJC Scopus subject areas

  • Organic Chemistry
  • Inorganic Chemistry
  • Electrochemistry
  • Drug Discovery
  • Physical and Theoretical Chemistry

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