Ligations of O-acyl threonine units to give native peptides via 5-, 8-, 9- and 10-membered cyclic transition states

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

N-Acyl threonine isopeptides undergo acyl transfer in chemical ligations via 5-, 8-, 9- and 10-membered cyclic transition states to yield natural peptides, representing the first examples of successful isopeptide ligations from N-acyl threonine units.

Original languageEnglish (US)
Pages (from-to)9-18
Number of pages10
JournalArkivoc
Volume2015
Issue number4
DOIs
StatePublished - Sep 19 2014

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Threonine
Peptides

Keywords

  • Acylation
  • Benzotriazole
  • Chemical ligation
  • Peptide
  • Threonine

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Ligations of O-acyl threonine units to give native peptides via 5-, 8-, 9- and 10-membered cyclic transition states. / Panda, Siva S.

In: Arkivoc, Vol. 2015, No. 4, 19.09.2014, p. 9-18.

Research output: Contribution to journalArticle

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