Abstract
N-Acyl threonine isopeptides undergo acyl transfer in chemical ligations via 5-, 8-, 9- and 10-membered cyclic transition states to yield natural peptides, representing the first examples of successful isopeptide ligations from N-acyl threonine units.
Original language | English (US) |
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Pages (from-to) | 9-18 |
Number of pages | 10 |
Journal | Arkivoc |
Volume | 2015 |
Issue number | 4 |
DOIs | |
State | Published - Sep 19 2014 |
Keywords
- Acylation
- Benzotriazole
- Chemical ligation
- Peptide
- Threonine
ASJC Scopus subject areas
- Organic Chemistry