Light and electron microscopic evaluaton of canine hearts orthotopically transplanted after 24 hours of extracorporeal preservation

M. Tago, R. Subramanian, M. P. Kaye

Research output: Contribution to journalArticle

3 Scopus citations


The hearts of 19 dogs were subjected to in vitro, moderately hypothermic, whole blood perfusion through the aorta for 24 hours. Sixteen of the hearts were reimplanted into recipient animals in the conventional orthotopic fashion and three were subjected to histologic study without reimplantation. Fourteen of the 16 reimplanted hearts successfully supported the recipients. Histologic and ultrastructural studies of the reimplanted hearts 24 hours and 7 days after implantation demonstrated good preservation of cellular and ultracellular structures. Some mild widening of the interstitium was noted.

Original languageEnglish (US)
Pages (from-to)912-919
Number of pages8
JournalJournal of Thoracic and Cardiovascular Surgery
Issue number6
Publication statusPublished - Dec 1 1983


ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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