Liquid chromatography determination of amino acids by precolumn fluorescence derivatization with acridone-N-acetyl chloride

Jin Mao You, Xingjun Fan, Qing Yu Ou, Qing Cun Zhu

Research output: Contribution to journalArticle

Abstract

A sensitive liquid Chromatographic method for the detection of amino acids with precolumn fluorescence derivatization with acridone-N-acetyl chloride has been developed. Amino acid derivatives were eluted in 40 min with good reproducibility. The relative standard deviations (n=6) at an analytical concentration of 50 pmol are < 4%. The method described is also suitable for the analysis of amino acids in different biological samples.

Original languageEnglish (US)
Pages (from-to)657-660
Number of pages4
JournalChinese Chemical Letters
Volume9
Issue number7
StatePublished - Dec 1 1998
Externally publishedYes

Keywords

  • Acridone-N-acetyl Chloride
  • Amino acids
  • Derivatization
  • Liquid chromatography

ASJC Scopus subject areas

  • Chemistry(all)

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