Localization of temporal lobe seizures with quantitative EEG

Anthony M. Murro, Yong D. Park, Don W. King, Brian B. Gallagher, Joseph R. Smith, Kimford J. Meador, Wanda Littelton

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

In this study, we describe a quantitative EEG method for localization of seizure onset in 29 patients with temporal lobe epilepsy. We used right-left differences in relative power and a logistic regression to predict the side of seizure onset. The optimum bipolar channels were T4-T6/T3-T5 and the optimum frequency band was 4-10.5 Hz. Using a threshold probability of 0.75 for classification, the best quantitative EEG method classified 23 patients (79%) correctly, 2 patients (7%) incorrectly, and 4 patients (14%) as undetermined localization. In comparison, 3 electroencephalographers visually interpreted these same EEGs and classified 20-25 patients (69-86%) correctly, 1 patient (3%) incorrectly and 3-8 patients (10-28%) as undetermined localization. In the 8 patients classified as undetermined localization by at least one interpreter, the quantitative EEG method classified 5 patients correctly, 1 patient incorrectly and 2 patients as undetermined localization. These results suggest that quantitative EEG might improve the reliability of ictal EEG localization and potentially reduce the need for invasive intracranial EEG monitoring.

Original languageEnglish (US)
Pages (from-to)88-93
Number of pages6
JournalElectroencephalography and Clinical Neurophysiology
Volume86
Issue number2
DOIs
StatePublished - Feb 1993

Fingerprint

Temporal Lobe
Electroencephalography
Seizures
Temporal Lobe Epilepsy
Logistic Models
Stroke

Keywords

  • Discriminant analysis
  • Electroencephalography
  • Epilepsy
  • Fourier analysis
  • Seizure
  • Temporal lobe

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

Cite this

Localization of temporal lobe seizures with quantitative EEG. / Murro, Anthony M.; Park, Yong D.; King, Don W.; Gallagher, Brian B.; Smith, Joseph R.; Meador, Kimford J.; Littelton, Wanda.

In: Electroencephalography and Clinical Neurophysiology, Vol. 86, No. 2, 02.1993, p. 88-93.

Research output: Contribution to journalArticle

Murro, Anthony M. ; Park, Yong D. ; King, Don W. ; Gallagher, Brian B. ; Smith, Joseph R. ; Meador, Kimford J. ; Littelton, Wanda. / Localization of temporal lobe seizures with quantitative EEG. In: Electroencephalography and Clinical Neurophysiology. 1993 ; Vol. 86, No. 2. pp. 88-93.
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