Long-term management of craniofacial osteosarcoma

Erh Kang Chou, Chun Shin Chang, Philip Kuo Ting Chen, Yu Ray Chen, Jack C Yu, Shih Ming Jung, Sophia Chia Ning Chang

Research output: Contribution to journalArticle

8 Scopus citations


Primary osteosarcoma of the calvarium is rare. A 22-year-old female patient was admitted for a progressively enlarging, indurated mass under her scalp for 6 months. A computed tomographic scan revealed a 4 × 3 × 2-cm osteolytic lesion over the right parietal cortex with a sunburst appearance. The patient underwent en bloc tumor resection using bicortical parietal craniectomy with a 2-cm margin of normal bone, including the tightly adherent periosteum over the tumor. Immediate cranioplasty was performed with split-thickness autogenous calvarial bone grafts. Histopathologic examination showed the tumor to be a primary high-grade osteosarcoma of the skull. She received postoperative chemotherapy. She has recovered well and remains without any evidence of disease at her most recent, 8-year follow-up. The key to disease-free survival in treating primary osteosarcoma of the calvarium is complete surgical resection with immediate reconstruction followed by adjuvant chemotherapy.

Original languageEnglish (US)
Pages (from-to)406-409
Number of pages4
JournalJournal of Craniofacial Surgery
Issue number2
StatePublished - Mar 1 2009


  • Calvarial bone graft
  • Craniectomy
  • Osteosarcoma

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

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    Chou, E. K., Chang, C. S., Chen, P. K. T., Chen, Y. R., Yu, J. C., Jung, S. M., & Chang, S. C. N. (2009). Long-term management of craniofacial osteosarcoma. Journal of Craniofacial Surgery, 20(2), 406-409. https://doi.org/10.1097/SCS.0b013e31819b9641