Low-density lipoprotein receptor-related protein 4 (LRP4) is a member of the low-density lipoprotein receptor (LDLR) family. Recent studies have revealed multiple functions and complex signaling mechanisms of LRP4 in different organs and tissues. LPR4 mutation or malfunction has been implicated in neurological disorders including congenital myasthenic syndrome, myasthenia gravis, and diseases of bone or kidney. copy; 2015 Elsevier Inc.
- Low-density lipoprotein receptor-related protein 4
- Myasthenia gravis
- Neuromuscular junction
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism