LRP4 in neuromuscular junction and bone development and diseases

Chengyong Shen, Wen Cheng Xiong, Lin Mei

Research output: Contribution to journalReview article

23 Scopus citations

Abstract

Low-density lipoprotein receptor-related protein 4 (LRP4) is a member of the low-density lipoprotein receptor (LDLR) family. Recent studies have revealed multiple functions and complex signaling mechanisms of LRP4 in different organs and tissues. LPR4 mutation or malfunction has been implicated in neurological disorders including congenital myasthenic syndrome, myasthenia gravis, and diseases of bone or kidney. copy; 2015 Elsevier Inc.

Original languageEnglish (US)
Pages (from-to)101-108
Number of pages8
JournalBone
Volume80
DOIs
Publication statusPublished - Nov 1 2015

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Keywords

  • Bone
  • Low-density lipoprotein receptor-related protein 4
  • Myasthenia gravis
  • Neuromuscular junction

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Physiology
  • Histology

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