M1 muscarinic receptors modify oxidative stress response to acetaminophen-induced acute liver injury

Medicine & Life Sciences

• Muscarinic M1 Receptors 100%
• Acetaminophen 73%
• Oxidative Stress 50%
• Liver 35%
• Wounds and Injuries 33%
• Hepatocytes 31%
• N-(3-oxo-3-(4-(pyridin-4-yl)piperazin-1-yl)propyl)benzo(c)(1,2,5)thiadiazole-4-sulfonamide 13%
• 3-nitrotyrosine 8%
• Muscarinic Antagonists 7%
• Automobiles 6%
• Muscarinic Receptors 6%
• DNA Fragmentation 6%
• Metabolic Networks and Pathways 6%
• Alanine Transaminase 6%
• Glutathione 5%
• Necrosis 4%
• Poisons 4%
• Hemorrhage 4%
• Cytokines 3%
• Injections 3%
• Therapeutics 3%
• Serum 2%
• In Vitro Techniques 2%

Chemical Compounds

• Parasympathomimetic Agent 86%
• Oxidative Stress 68%
• Muscarinic M1 Receptor Antagonist 12%
• Intrahepatic 9%
• Nitrotyrosine 9%
• Alanine 5%
• Glutathione 5%
• Fragmentation 4%
• Metabolic 4%
• Toxic 4%