Magnetohydrodynamic Voltage Recorder for Comparing Peripheral Blood Flow

Kevin J. Wu, T. Stan Gregory, Michael C. Lastinger, Jonathan R Murrow, Zion Tsz Ho Tse

Research output: Contribution to journalArticle

Abstract

Blood flow is a clinical metric for monitoring of cardiovascular diseases but current measurements methods are costly or uncomfortable for patients. It was shown that the interaction of the magnetic field (B0) during MRI and blood flow in the body, through the magnetohydrodynamic (MHD) effect, produce voltages (VMHD) observable through intra-MRI electrocardiography (ECG), which are correlated with regional blood flow. This study shows the reproducibility of VMHD outside the MRI and its application in a portable flow monitoring device. To recreate this interaction outside the MRI, a static neodymium magnet (0.4T) was placed in between two electrodes to induce the VMHD in a single lead ECG measurement. VMHD was extracted, and integrated over to obtain a stroke volume metric. A smartphone-enabled device utilizing this interaction was developed in order to create a more accessible method of obtaining blood flow measurements. The portable device displayed a <6% error compared to a commercial recorder, and was able to successfully record VMHD using the 0.4T magnet. Exercise stress testing showed a VMHD increase of 23% in healthy subjects, with an 81% increase in the athlete. The study demonstrates a new device utilizing MHD interactions with body circulation to obtain blood flow metrics.

Original languageEnglish (US)
Pages (from-to)2298-2308
Number of pages11
JournalAnnals of Biomedical Engineering
Volume45
Issue number10
DOIs
StatePublished - Oct 1 2017
Externally publishedYes

Fingerprint

Magnetohydrodynamics
Blood
Magnetic resonance imaging
Electric potential
Electrocardiography
Magnets
Neodymium
Monitoring
Smartphones
Electric current measurement
Flow measurement
Lead
Magnetic fields
Electrodes
Testing

Keywords

  • Blood flow
  • ECG
  • Electrocardiography
  • MHD effect
  • Smartphone

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Magnetohydrodynamic Voltage Recorder for Comparing Peripheral Blood Flow. / Wu, Kevin J.; Gregory, T. Stan; Lastinger, Michael C.; Murrow, Jonathan R; Tse, Zion Tsz Ho.

In: Annals of Biomedical Engineering, Vol. 45, No. 10, 01.10.2017, p. 2298-2308.

Research output: Contribution to journalArticle

Wu, Kevin J. ; Gregory, T. Stan ; Lastinger, Michael C. ; Murrow, Jonathan R ; Tse, Zion Tsz Ho. / Magnetohydrodynamic Voltage Recorder for Comparing Peripheral Blood Flow. In: Annals of Biomedical Engineering. 2017 ; Vol. 45, No. 10. pp. 2298-2308.
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