TY - JOUR
T1 - Malignant fibrous histiocytoma
T2 - Report of five cases and a review of the literature
AU - Zaren, Howard A.
AU - Delaurentis, Dominic
AU - Paskin, David L.
AU - Lerner, Harvey J.
PY - 1978
Y1 - 1978
N2 - Five cases of malignant fibrous histiocytoma are presented and the relevant literature is reviewed. All the patients had locally extensive tumor or eventual recurrent or metastatic disease. Determining malignancy by histologic criteria is difficult. Therefore, histologic, gross, and clinical behavior of the tumor is important. Though the role of radiation therapy and chemotherapy is not yet established, it appears that at least wide “cancer resection,” if possible, is the treatment of choice. The unusually high incidence of nonresectable, recurrent, or metastatic disease in retroperitoneal histiocytomas raises the question as to whether all three modalities of therapy should be used in the treatment of tumors at this particular site.
AB - Five cases of malignant fibrous histiocytoma are presented and the relevant literature is reviewed. All the patients had locally extensive tumor or eventual recurrent or metastatic disease. Determining malignancy by histologic criteria is difficult. Therefore, histologic, gross, and clinical behavior of the tumor is important. Though the role of radiation therapy and chemotherapy is not yet established, it appears that at least wide “cancer resection,” if possible, is the treatment of choice. The unusually high incidence of nonresectable, recurrent, or metastatic disease in retroperitoneal histiocytomas raises the question as to whether all three modalities of therapy should be used in the treatment of tumors at this particular site.
KW - malignant fibrous histiocytoma
KW - multidiscipline treatment
KW - sarcoma
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U2 - 10.1002/jso.2930100508
DO - 10.1002/jso.2930100508
M3 - Article
C2 - 215843
AN - SCOPUS:0018167063
SN - 0022-4790
VL - 10
SP - 431
EP - 439
JO - Journal of Surgical Oncology
JF - Journal of Surgical Oncology
IS - 5
ER -