Management of nerve sheath tumors arising in the sympathetic chain

Surbhi Jain, Kristin Houseknecht, Amyn M. Rojiani, Matthias Setzer, Frank D. Vrionis

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: Extradural schwannomas arising from the sympathetic chain are uncommon benign nerve sheath tumors. We present our experience with three patients having such tumors located in the cervical, thoracic and lumbar regions and we describe clinical presentation, surgical treatment, and outcomes. Methods: Between 2002 and 2006, the medical records of three patients with pathologically proven sympathetic schwannomas at the Moffitt Cancer Center were reviewed retrospectively. Results: The three patients were female, with a mean age of 44 years. Presentation and symptomatology varied between patients, and radiographic findings were not diagnostic. Complete excision of tumors was performed in all three patients without added morbidity or mortality. Surgical observation, histopathology, and immunohistochemistry confirmed the tumors to be schwannomas arising from the sympathetic chain. The schwannomas had a mean diameter of 3.2 cm and were all benign. At a mean follow-up of 21 months following resection, all patients remained free of disease recurrence. Conclusions: Sympathetic schwannomas are rare tumors that are difficult to diagnose preoperatively. Diagnosis relies on clinical suspicion, and confirmation is often obtained by means of surgical pathology. Long-term surveillance is not recommended and surgical excision should be considered for this tumor, even though the tumor is considered benign and recurrence is rare.

Original languageEnglish (US)
Pages (from-to)352-357
Number of pages6
JournalCancer Control
Volume15
Issue number4
DOIs
StatePublished - Oct 2008

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Nerve Sheath Neoplasms
Neurilemmoma
Neoplasms
Recurrence
Lumbosacral Region
Surgical Pathology
Medical Records
Thorax
Immunohistochemistry
Observation
Morbidity
Mortality

ASJC Scopus subject areas

  • Hematology
  • Oncology

Cite this

Management of nerve sheath tumors arising in the sympathetic chain. / Jain, Surbhi; Houseknecht, Kristin; Rojiani, Amyn M.; Setzer, Matthias; Vrionis, Frank D.

In: Cancer Control, Vol. 15, No. 4, 10.2008, p. 352-357.

Research output: Contribution to journalArticle

Jain, S, Houseknecht, K, Rojiani, AM, Setzer, M & Vrionis, FD 2008, 'Management of nerve sheath tumors arising in the sympathetic chain', Cancer Control, vol. 15, no. 4, pp. 352-357. https://doi.org/10.1177/107327480801500410
Jain, Surbhi ; Houseknecht, Kristin ; Rojiani, Amyn M. ; Setzer, Matthias ; Vrionis, Frank D. / Management of nerve sheath tumors arising in the sympathetic chain. In: Cancer Control. 2008 ; Vol. 15, No. 4. pp. 352-357.
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