Maternal impact on egg development in lymnaea stagnalis: A growth factor is produced by the albumen gland in the reproductive tract

Gregg Thomas Nagle, David B.G. Akalal, Sherry D. Painter

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

In the freshwater snail Lymnaea stagnalis, perivitellin fluid is the main source of nutrition for developing embryos; it contains predominantly galactogen and proteins. The fluid is produced by the albumen gland, a large exocrine organ in the female reproductive tract. To further define the protein products of this gland and provide more information about the maternal contribution to egg development, albumen glands were extracted and the extracts purified by reversed-phase HPLC. One major HPLC peak fraction exhibited neurotrophic activity when bioassayed on identified Lymnaea neurons in vitro; it has been partially sequenced and has the highest degree of sequence identity with epidermal growth factor (EGF). These results demonstrate that a growth factor with neurotrophic activity is produced by the albumen gland, and is packaged along with the eggs to serve a growth-promoting function in the embryo.

Original languageEnglish (US)
Pages (from-to)171-174
Number of pages4
JournalInvertebrate Reproduction and Development
Volume36
Issue number1-3
DOIs
StatePublished - Jan 1 1999
Externally publishedYes

Fingerprint

Lymnaea
Lymnaea stagnalis
growth factors
Ovum
Intercellular Signaling Peptides and Proteins
embryo (animal)
Embryonic Structures
High Pressure Liquid Chromatography
Mothers
protein products
epidermal growth factor
Snails
reversed-phase high performance liquid chromatography
Fresh Water
Epidermal Growth Factor
Eggs
snails
Proteins
high performance liquid chromatography
neurons

Keywords

  • Albumen gland
  • Freshwater mollusk
  • Growth factor
  • Reproduction

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Developmental Biology

Cite this

Maternal impact on egg development in lymnaea stagnalis : A growth factor is produced by the albumen gland in the reproductive tract. / Nagle, Gregg Thomas; Akalal, David B.G.; Painter, Sherry D.

In: Invertebrate Reproduction and Development, Vol. 36, No. 1-3, 01.01.1999, p. 171-174.

Research output: Contribution to journalArticle

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