Matrix Metalloproteinases and their Inhibitors - Friend or Foe

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)
Original languageEnglish (US)
Title of host publicationTumor Microenvironment
PublisherJohn Wiley and Sons
Pages53-76
Number of pages24
ISBN (Print)9780470749968
DOIs
StatePublished - Aug 31 2010

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Tissue Inhibitor of Metalloproteinases
Matrix Metalloproteinase Inhibitors

Keywords

  • Invasive and metastatic activities of cancer cells - contributing morbidity and mortality
  • MMP impact on tumor microenvironment and growth
  • Mammalian family of matrix metalloproteinases
  • Matrilysins, MMP-7 and MMP-26 - roles - in degradation and processing of ECM and non-ECM proteins
  • Matrix metalloproteinases and their inhibitors - friend or foe
  • Modulating change within physiologic and tumor microenvironment - matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs)
  • Pleiotropic nature of MMPs - diversity of functions in cancer progression
  • Targets and substrates of MMP action - cellular or extracellular
  • Tissue inhibitors of matrix metalloproteinases
  • Tumor-associated fibroblasts - role in cancer progression and angiogenesis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Matrix Metalloproteinases and their Inhibitors - Friend or Foe. / Rojiani, Mumtaz V; Wiranowska, Marzenna; Rojiani, Amyn Mohammed.

Tumor Microenvironment. John Wiley and Sons, 2010. p. 53-76.

Research output: Chapter in Book/Report/Conference proceedingChapter

Rojiani, Mumtaz V ; Wiranowska, Marzenna ; Rojiani, Amyn Mohammed. / Matrix Metalloproteinases and their Inhibitors - Friend or Foe. Tumor Microenvironment. John Wiley and Sons, 2010. pp. 53-76
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