Measurements of Strontium Levels in Human Bone In Vivo Using Portable X-ray Fluorescence (XRF)

Aaron J. Specht, Farshad Mostafaei, Yanfen Lin, Jian Xu, Linda H. Nie

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

Measurement of bone strontium (Sr) is vital to determining the effectiveness of Sr supplementation, which is commonly used for the treatment of osteoporosis. Previous technology uses radioisotope sources and bulky equipment to measure bone Sr. This study demonstrates the effectiveness of portable X-ray fluorescence (XRF) for bone Sr measurement and validates it using data from a population of 238 children. We identified correlations between bone Sr and age in our participants.

Original languageEnglish (US)
Pages (from-to)1962-1968
Number of pages7
JournalApplied Spectroscopy
Volume71
Issue number8
DOIs
StatePublished - Aug 1 2017
Externally publishedYes

Keywords

  • X-ray fluorescence
  • XRF
  • bone
  • in vivo
  • strontium

ASJC Scopus subject areas

  • Instrumentation
  • Spectroscopy

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