Mechanisms of obesity-induced hypertension

John E. Hall; Dion H. Zappe; Magdalena Alonso-Galicia; Joey P. Granger; Michael W. Brands; Salah E. Kassab

Mechanisms of obesity-induced hypertension

John E. Hall, Dion H. Zappe, Magdalena Alonso-Galicia, Joey P. Granger, Michael W. Brands, Salah E. Kassab

Research output: Contribution to journal › Article › peer-review

Abstract

Obesity is a major cause of human essential hypertension. Recent studies point toward increased renal tubular reabsorption and abnormal renal pressure natriuresis in mediating obesity hypertension. The mechanisms for these renal changes appear to be multifactorial, including activation of the sympathetic nervous system and altered intrarenal histology, which compresses the renal medulla.

Original language	English (US)
Pages (from-to)	255-261
Number of pages	7
Journal	News in Physiological Sciences
Volume	11
Issue number	6
State	Published - Dec 1 1996
Externally published	Yes

ASJC Scopus subject areas

Physiology

Cite this

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title = "Mechanisms of obesity-induced hypertension",

abstract = "Obesity is a major cause of human essential hypertension. Recent studies point toward increased renal tubular reabsorption and abnormal renal pressure natriuresis in mediating obesity hypertension. The mechanisms for these renal changes appear to be multifactorial, including activation of the sympathetic nervous system and altered intrarenal histology, which compresses the renal medulla.",

author = "Hall, {John E.} and Zappe, {Dion H.} and Magdalena Alonso-Galicia and Granger, {Joey P.} and Brands, {Michael W.} and Kassab, {Salah E.}",

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language = "English (US)",

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AU - Hall, John E.

AU - Zappe, Dion H.

AU - Alonso-Galicia, Magdalena

AU - Granger, Joey P.

AU - Brands, Michael W.

AU - Kassab, Salah E.

PY - 1996/12/1

Y1 - 1996/12/1

N2 - Obesity is a major cause of human essential hypertension. Recent studies point toward increased renal tubular reabsorption and abnormal renal pressure natriuresis in mediating obesity hypertension. The mechanisms for these renal changes appear to be multifactorial, including activation of the sympathetic nervous system and altered intrarenal histology, which compresses the renal medulla.

AB - Obesity is a major cause of human essential hypertension. Recent studies point toward increased renal tubular reabsorption and abnormal renal pressure natriuresis in mediating obesity hypertension. The mechanisms for these renal changes appear to be multifactorial, including activation of the sympathetic nervous system and altered intrarenal histology, which compresses the renal medulla.

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M3 - Article

AN - SCOPUS:0030372652

SN - 1548-9213

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JO - Physiology

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Mechanisms of obesity-induced hypertension

Abstract

ASJC Scopus subject areas

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