Mechanisms of obesity-induced hypertension

John E. Hall, Dion H. Zappe, Magdalena Alonso-Galicia, Joey P. Granger, Michael W. Brands, Salah E. Kassab

Research output: Contribution to journalArticle

34 Scopus citations


Obesity is a major cause of human essential hypertension. Recent studies point toward increased renal tubular reabsorption and abnormal renal pressure natriuresis in mediating obesity hypertension. The mechanisms for these renal changes appear to be multifactorial, including activation of the sympathetic nervous system and altered intrarenal histology, which compresses the renal medulla.

Original languageEnglish (US)
Pages (from-to)255-261
Number of pages7
JournalNews in Physiological Sciences
Issue number6
StatePublished - Dec 1 1996
Externally publishedYes

ASJC Scopus subject areas

  • Physiology

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    Hall, J. E., Zappe, D. H., Alonso-Galicia, M., Granger, J. P., Brands, M. W., & Kassab, S. E. (1996). Mechanisms of obesity-induced hypertension. News in Physiological Sciences, 11(6), 255-261.