Mechanisms of obesity-induced hypertension

John E. Hall, Dion H. Zappe, Magdalena Alonso-Galicia, Joey P. Granger, Michael W. Brands, Salah E. Kassab

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34 Scopus citations

Abstract

Obesity is a major cause of human essential hypertension. Recent studies point toward increased renal tubular reabsorption and abnormal renal pressure natriuresis in mediating obesity hypertension. The mechanisms for these renal changes appear to be multifactorial, including activation of the sympathetic nervous system and altered intrarenal histology, which compresses the renal medulla.

Original languageEnglish (US)
Pages (from-to)255-261
Number of pages7
JournalNews in Physiological Sciences
Volume11
Issue number6
Publication statusPublished - Dec 1 1996
Externally publishedYes

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ASJC Scopus subject areas

  • Physiology

Cite this

Hall, J. E., Zappe, D. H., Alonso-Galicia, M., Granger, J. P., Brands, M. W., & Kassab, S. E. (1996). Mechanisms of obesity-induced hypertension. News in Physiological Sciences, 11(6), 255-261.