Medical and surgical considerations in patients wit Samter's triad

K. Christopher McMains, Stilianos E Kountakis

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Background: The aim of this study was to report on objective and subjective outcomes of patients with Samter's triad (ST) treated with functional endoscopic sinus surgery (FESS), and correlate these results with aspirin desensitization (DS) in patients. Methods: We performed a retrospective analysis of prospectively collected data in 15 patients requiring revision FESS after failing maximum medical therapy and prior sinus surgery for chronic rhinosinusitis in the context of ST. Five patients underwent aspirin DS and 10 patients did not (non-DS). These patients represent a subset of patients previously reported who were treated in a tertiary rhinology setting over a 3-year period (1999-2001). CT scans were graded according to the Lund-Mackay grading scale and symptom scores were assessed using the Sino-Nasal Outcome Test (SNOT-20). Endoscopy was scored according to the Rhinosinusitis Task Force methodology. All patients had a minimum 2-year follow-up. Results: Preoperative CT scores were 20.1 ± 1.9 for non-DS patients and 20.4 ± 2.0 for DS patients (p = NS). Preoperative and postoperative SNOT-20 scores for non-DS patients were 31.8 ± 3.9 and 8.8 ± 1.7, respectively, as compared with 32.0 ± 3.6 and 7.3 ± 1.7 for DS patients (p = NS). Preoperative and postoperative endoscopy scores for non-DS patients were 7.6 ± 1.2 and 2.0 ± 0.4, respectively, as compared with 7.6 ± 1.3 and 1.1 ± 0.4 for DS patients (p = NS). Of DS patients, none required additional surgery whereas 8 of 10 non-DS patients required additional revision during the follow-up period (p = 0.003). Conclusion: Revision FESS benefits patients with ST; however, the addition of aspirin DS decreases the likelihood that patients with ST will require additional surgical intervention over a 2-year period.

Original languageEnglish (US)
Pages (from-to)573-576
Number of pages4
JournalAmerican Journal of Rhinology
Volume20
Issue number6
DOIs
StatePublished - Nov 1 2006

Fingerprint

Wit and Humor
Aspirin
Endoscopy

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Medical and surgical considerations in patients wit Samter's triad. / McMains, K. Christopher; Kountakis, Stilianos E.

In: American Journal of Rhinology, Vol. 20, No. 6, 01.11.2006, p. 573-576.

Research output: Contribution to journalArticle

@article{fc064b24649d4b17b8d668c02edb3df6,
title = "Medical and surgical considerations in patients wit Samter's triad",
abstract = "Background: The aim of this study was to report on objective and subjective outcomes of patients with Samter's triad (ST) treated with functional endoscopic sinus surgery (FESS), and correlate these results with aspirin desensitization (DS) in patients. Methods: We performed a retrospective analysis of prospectively collected data in 15 patients requiring revision FESS after failing maximum medical therapy and prior sinus surgery for chronic rhinosinusitis in the context of ST. Five patients underwent aspirin DS and 10 patients did not (non-DS). These patients represent a subset of patients previously reported who were treated in a tertiary rhinology setting over a 3-year period (1999-2001). CT scans were graded according to the Lund-Mackay grading scale and symptom scores were assessed using the Sino-Nasal Outcome Test (SNOT-20). Endoscopy was scored according to the Rhinosinusitis Task Force methodology. All patients had a minimum 2-year follow-up. Results: Preoperative CT scores were 20.1 ± 1.9 for non-DS patients and 20.4 ± 2.0 for DS patients (p = NS). Preoperative and postoperative SNOT-20 scores for non-DS patients were 31.8 ± 3.9 and 8.8 ± 1.7, respectively, as compared with 32.0 ± 3.6 and 7.3 ± 1.7 for DS patients (p = NS). Preoperative and postoperative endoscopy scores for non-DS patients were 7.6 ± 1.2 and 2.0 ± 0.4, respectively, as compared with 7.6 ± 1.3 and 1.1 ± 0.4 for DS patients (p = NS). Of DS patients, none required additional surgery whereas 8 of 10 non-DS patients required additional revision during the follow-up period (p = 0.003). Conclusion: Revision FESS benefits patients with ST; however, the addition of aspirin DS decreases the likelihood that patients with ST will require additional surgical intervention over a 2-year period.",
author = "McMains, {K. Christopher} and Kountakis, {Stilianos E}",
year = "2006",
month = "11",
day = "1",
doi = "10.2500/ajr.2006.20.2913",
language = "English (US)",
volume = "20",
pages = "573--576",
journal = "American Journal of Rhinology and Allergy",
issn = "1945-8924",
publisher = "OceanSide Publications Inc.",
number = "6",

}

TY - JOUR

T1 - Medical and surgical considerations in patients wit Samter's triad

AU - McMains, K. Christopher

AU - Kountakis, Stilianos E

PY - 2006/11/1

Y1 - 2006/11/1

N2 - Background: The aim of this study was to report on objective and subjective outcomes of patients with Samter's triad (ST) treated with functional endoscopic sinus surgery (FESS), and correlate these results with aspirin desensitization (DS) in patients. Methods: We performed a retrospective analysis of prospectively collected data in 15 patients requiring revision FESS after failing maximum medical therapy and prior sinus surgery for chronic rhinosinusitis in the context of ST. Five patients underwent aspirin DS and 10 patients did not (non-DS). These patients represent a subset of patients previously reported who were treated in a tertiary rhinology setting over a 3-year period (1999-2001). CT scans were graded according to the Lund-Mackay grading scale and symptom scores were assessed using the Sino-Nasal Outcome Test (SNOT-20). Endoscopy was scored according to the Rhinosinusitis Task Force methodology. All patients had a minimum 2-year follow-up. Results: Preoperative CT scores were 20.1 ± 1.9 for non-DS patients and 20.4 ± 2.0 for DS patients (p = NS). Preoperative and postoperative SNOT-20 scores for non-DS patients were 31.8 ± 3.9 and 8.8 ± 1.7, respectively, as compared with 32.0 ± 3.6 and 7.3 ± 1.7 for DS patients (p = NS). Preoperative and postoperative endoscopy scores for non-DS patients were 7.6 ± 1.2 and 2.0 ± 0.4, respectively, as compared with 7.6 ± 1.3 and 1.1 ± 0.4 for DS patients (p = NS). Of DS patients, none required additional surgery whereas 8 of 10 non-DS patients required additional revision during the follow-up period (p = 0.003). Conclusion: Revision FESS benefits patients with ST; however, the addition of aspirin DS decreases the likelihood that patients with ST will require additional surgical intervention over a 2-year period.

AB - Background: The aim of this study was to report on objective and subjective outcomes of patients with Samter's triad (ST) treated with functional endoscopic sinus surgery (FESS), and correlate these results with aspirin desensitization (DS) in patients. Methods: We performed a retrospective analysis of prospectively collected data in 15 patients requiring revision FESS after failing maximum medical therapy and prior sinus surgery for chronic rhinosinusitis in the context of ST. Five patients underwent aspirin DS and 10 patients did not (non-DS). These patients represent a subset of patients previously reported who were treated in a tertiary rhinology setting over a 3-year period (1999-2001). CT scans were graded according to the Lund-Mackay grading scale and symptom scores were assessed using the Sino-Nasal Outcome Test (SNOT-20). Endoscopy was scored according to the Rhinosinusitis Task Force methodology. All patients had a minimum 2-year follow-up. Results: Preoperative CT scores were 20.1 ± 1.9 for non-DS patients and 20.4 ± 2.0 for DS patients (p = NS). Preoperative and postoperative SNOT-20 scores for non-DS patients were 31.8 ± 3.9 and 8.8 ± 1.7, respectively, as compared with 32.0 ± 3.6 and 7.3 ± 1.7 for DS patients (p = NS). Preoperative and postoperative endoscopy scores for non-DS patients were 7.6 ± 1.2 and 2.0 ± 0.4, respectively, as compared with 7.6 ± 1.3 and 1.1 ± 0.4 for DS patients (p = NS). Of DS patients, none required additional surgery whereas 8 of 10 non-DS patients required additional revision during the follow-up period (p = 0.003). Conclusion: Revision FESS benefits patients with ST; however, the addition of aspirin DS decreases the likelihood that patients with ST will require additional surgical intervention over a 2-year period.

UR - http://www.scopus.com/inward/record.url?scp=33845706675&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33845706675&partnerID=8YFLogxK

U2 - 10.2500/ajr.2006.20.2913

DO - 10.2500/ajr.2006.20.2913

M3 - Article

VL - 20

SP - 573

EP - 576

JO - American Journal of Rhinology and Allergy

JF - American Journal of Rhinology and Allergy

SN - 1945-8924

IS - 6

ER -