Meningeal Sarcomas

Nicholas G. Avgeropoulos, John W. Henson

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Meningeal sarcomas are rare tumors arising from the mesenchymal components of dura mater, adventitia of blood vessels, tela choridea, choroids plexus, and leptomeninges. This chapter reviews fibrosarcoma, mesenchymal chondrosarcoma, chondrosarcoma, rhabdomyosarcoma (RMS), leiomyosarcoma, meningeal sarcomatosis, malignant fibrous histiocytoma, angiosarcoma, liposarcoma, and osteosarcoma. Primary meningeal sarcomas should be considered in the differential diagnosis when encountering an aggressive dural neoplasm in a patient of any age. Upon histologic confirmation of the diagnosis, radiographic staging and cytologic examination of the cerebrospinal fluid should be strongly considered. Multimodal treatment includes maximum feasible resection, involved field radiation treatment and chemotherapy. Although the clinical course of certain "well-differentiated" sarcomas has been favorable, survival in general is poor.

Original languageEnglish (US)
Title of host publicationTextbook of Uncommon Cancer, Third Edition
PublisherJohn Wiley & Sons, Ltd
Pages626-637
Number of pages12
ISBN (Print)0470012021, 9780470012024
DOIs
StatePublished - Jul 11 2006
Externally publishedYes

Keywords

  • Chondrosarcoma
  • Fibrosarcoma
  • Meningeal
  • Mesenchymal
  • Sarcoma
  • Treatment

ASJC Scopus subject areas

  • Medicine(all)

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