TY - CHAP
T1 - Methylmercury exposure and health effects in humans: a worldwide concern.
AU - Mergler, Donna
AU - Anderson, Henry A.
AU - Chan, Laurie Hing Man
AU - Mahaffey, Kathryn R.
AU - Murray, Michael
AU - Sakamoto, Mineshi
AU - Stern, Alan H.
PY - 2007
Y1 - 2007
N2 - The paper builds on existing literature, highlighting current understanding and identifying unresolved issues about MeHg exposure, health effects, and risk assessment, and concludes with a consensus statement. Methylmercury is a potent toxin, bioaccumulated and concentrated through the aquatic food chain, placing at risk people, throughout the globe and across the socioeconomic spectrum, who consume predatory fish or for whom fish is a dietary mainstay. Methylmercury developmental neurotoxicity has constituted the basis for risk assessments and public health policies. Despite gaps in our knowledge on new bioindicators of exposure, factors that influence MeHg uptake and toxicity, toxicokinetics, neurologic and cardiovascular effects in adult populations, and the nutritional benefits and risks from the large number of marine and freshwater fish and fish-eating species, the panel concluded that to preserve human health, all efforts need to be made to reduce and eliminate sources of exposure.
AB - The paper builds on existing literature, highlighting current understanding and identifying unresolved issues about MeHg exposure, health effects, and risk assessment, and concludes with a consensus statement. Methylmercury is a potent toxin, bioaccumulated and concentrated through the aquatic food chain, placing at risk people, throughout the globe and across the socioeconomic spectrum, who consume predatory fish or for whom fish is a dietary mainstay. Methylmercury developmental neurotoxicity has constituted the basis for risk assessments and public health policies. Despite gaps in our knowledge on new bioindicators of exposure, factors that influence MeHg uptake and toxicity, toxicokinetics, neurologic and cardiovascular effects in adult populations, and the nutritional benefits and risks from the large number of marine and freshwater fish and fish-eating species, the panel concluded that to preserve human health, all efforts need to be made to reduce and eliminate sources of exposure.
U2 - 10.1579/0044-7447(2007)36[3:MEAHEI]2.0.CO;2
DO - 10.1579/0044-7447(2007)36[3:MEAHEI]2.0.CO;2
M3 - Chapter
C2 - 17408186
SN - 00447447
T3 - Ambio
SP - 3
EP - 11
BT - Ambio
ER -