Metoclopramide-induced Parkinsonism

K. D. Sethi, B. Patel, K. J. Meador

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Metoclopramide hydrochloride (Reglan) is a widely prescribed drug for treatment of upper gastrointestinal symptoms. Although the drug is relatively safe, a growing body of literature has noted movement disorders after its administration. We have reported six cases of metoclopramide-induced parkinsonism seen in consultation over a two-year period. Five of these six patients had renal failure. Their parkinsonism improved on discontinuation of metoclopramide therapy. Metoclopramide-induced parkinonism is not rare, and appropriate dose reduction in patients with renal failure will help reduce the incidence of this morbidity.

Original languageEnglish (US)
Pages (from-to)1581-1582
Number of pages2
JournalSouthern Medical Journal
Issue number12
StatePublished - Jan 1 1989

ASJC Scopus subject areas

  • Medicine(all)


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