MicroRNAs as regulators of prostate cancer metastasis

Divya Bhagirath, Thao Ly Yang, Rajvir Dahiya, Sharanjot Saini

Research output: Chapter in Book/Report/Conference proceedingChapter

9 Scopus citations


Prostate cancer causes significant morbidity in men and metastatic disease is a major cause of cancer related deaths. Prostate metastasis is controlled by various cellular intrinsic and extrinsic factors, which are often under the regulatory control of various metastasis-associated genes. Given the dynamic nature of metastatic cancer cells, the various factors controlling this process are themselves regulated by microRNAs which are small non-coding RNAs. Significant research work has shown differential microRNA expression in primary and metastatic prostate cancer suggesting their importance in prostate pathogenesis. We will review the roles of different microRNAs in controlling the various steps in prostate metastasis.

Original languageEnglish (US)
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Number of pages18
StatePublished - 2018
Externally publishedYes

Publication series

NameAdvances in Experimental Medicine and Biology
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019


  • ECM
  • EMT
  • Metastasis
  • Prostate cancer
  • microRNAs

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


Dive into the research topics of 'MicroRNAs as regulators of prostate cancer metastasis'. Together they form a unique fingerprint.

Cite this