Microwave-assisted synthesis of biotin conjugates with quinolone antibiotics via amino acids

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Benzotriazole-activated biotin was utilized as a versatile building block for the efficient and convenient synthesis of novel biotin conjugates with quinolone antibiotics via amino acid linkers under microwave irradiation. The products are obtained in yields of 70-91% with retention of chirality.

Original languageEnglish (US)
Article numberSS-2014-M0006-OP
Pages (from-to)1511-1517
Number of pages7
JournalSynthesis (Germany)
Volume46
Issue number11
DOIs
StatePublished - 2014

Keywords

  • amino acid
  • antibiotics
  • benzotriazole method
  • biotin
  • microwave-assisted reaction
  • vitamins

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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